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Recombinant Chicken Transcriptional repressor CTCF (CTCF), partial

Recombinant Chicken Transcriptional repressor CTCF (CTCF), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

CTCF

Purity

>85% (SDS-PAGE)

Target Names

CTCF

Uniprot NO.

Q08705

Species

Gallus gallus (Chicken)

Source

Yeast

Expression Region

1-728

Target Protein Sequence

MEGEAVEAIV EESETFIKGK ERKTYQRRRE GGQEDEACHI APNQADGGEV VQDVNSGVQM VMMEHLDPTL LQMKTEVMEG AVPQETEATV DDTQIITLQV VNMEEQPINL GELQLVQVPV PVTVPVATTS VEELQGAYEN EVSKGGLQEG EPMICHTLPL PEGFQVVKVG ANGEVETLEQ GELQPQEDPN WQKDPDYQPP AKKTKKNKKS KLRYTEEGKD VDVSVYDFEE EQQEGLLSEV NAEKVVGNMK PPKPTKIKKK GVKKTFQCEL CSYTCPRRSN LDRHMKSHTD ERPHKCHLCG RAFRTVTLLR NHLNTHTGTR PHKCPDCDMA FVTSGELVRH RRYKHTHEKP FKCSMCDYAS VEVSKLKRHI RSHTGERPFQ CSLCSYASRD TYKLKRHMRT HSGEKPYECY ICHARFTQSG TMKMHILQKH TENVAKFHCP HCDTVIARKS DLGVHLRKQH SYIEQGKKCR YCDAVFHERY ALIQHQKSHK NEKRFKCDQC DYACRQERHM VMHKRTHTGE KPYACSHCDK TFRQKQLLDM HFKRYHDPNF VPAAFVCSKC GKTFTRRNTM ARHADNCSGL DGGEGENGGE TKKGKRGRKR KMRSKKEDSS DSEENAEPDL DDNEDEEETA VEIEAEPEVS AEAPAPPPSK KRRGRPPGKA ATQTKQSQPA AIIQVEDQNT GEIENIIVEV KKEPDAETVE EEEEAQPAVV EAPNGDLTPE MILSMMDR
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Acts as both a transcriptional activator and repressor of the MYC gene.

Gene References into Functions

CTCF is contributing to a specific chromatin configuration that is necessary for differential alpha-globin gene expression during development. PMID:23880533
a DNA sequence element, HS4, at the 5' end of the beta-globin locus, contains a binding site for CTCF that is necessary and sufficient for insulator action PMID:15169959
CTCF blocks the binding of YB-1 to its DNA recognition sequences in vitro, thus providing a possible mechanism of regulation of YB-1 activation of the 5-HTT VNTR by CTCF. PMID:15229244
CTCF-dependent silencer stabilizes the level of ggPRX gene transcription in erythroid cells PMID:16478981