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Recombinant Chicken Transcription factor E2F1 (E2F1)

Recombinant Chicken Transcription factor E2F1 (E2F1)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

E2F1

Purity

>85% (SDS-PAGE)

Target Names

E2F1

Uniprot NO.

Q90977

Alternative Names

E2F1Transcription factor E2F1; E2F-1

Species

Gallus gallus (Chicken)

Source

Yeast

Expression Region

1-403

Target Protein Sequence

MATAGGAAGL AALLGGASPH LLIVSASEEP AGGCRPDADL LLFATPQPSR PGPAPRRPAL GRPPVKRKLN LETDHQYIAE SLPAARGRAR IPGRGAKSPG EKSRYETSLN LTTKRFLELL SQSPDGVVDL NWAAEVLKVQ KRRIYDITNV LEGIQLITKK SKNNIQWLGS QVAAGASSRQ RLLEKELRDL QAAERQLDDL IQTCTVRLRL LTEDPSNQHA AYVTCQDLRS IVDPSEQMVM VIKAPPETQL QVSDPGEAFQ VSVRSTQGPI DVFLCPEDSS GVCSPVKSPF KAPAEELSPG SSQQRASPLL HSAQDVNMLL PEALLPGTAL PTKCPTEDVS LSPLASMDTL LEHGKDDFPG FLADEFIALS PPQPQDYHFG LEEGEGISEL FDCDFGDFTH LDF
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function(From Uniprot)

Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53/p53-dependent apoptosis. Blocks adipocyte differentiation by binding to specific promoters repressing CEBPA binding to its target gene promoters. Positively regulates transcription of RRP1B.

Gene References into Functions

E2F1 can bind directly to promoters of the miR-17~92 and miR-106a~363 clusters and activate their transcription, and E2F1 protein expression is correlated with the expression of pri-miR-17~92 and pri-miR-106a~363 during myoblast differentiation. PMID:27282946

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Subcellular Location

Nucleus.

Protein Families

E2F/DP family

Database Links

UNIGENE: Gga.3213

KEGG: gga:396142

STRING: 9031.ENSGALP00000004806

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