Recombinant Chicken Signal transducer and activator of transcription 3 (STAT3), partial

Product Details

Abbreviation
STAT3
Purity
>85% (SDS-PAGE)
Target Names
STAT3
Uniprot NO.
Species
Gallus gallus (Chicken)
Source
Yeast
Expression Region
1-771
Target Protein Sequence
MAQWNQLQQL DTRYLEQLHQ LYSDSFPMEL RQFLAPWIES QDWAYAANKE SHATLVFHNL LGEIDQQYSR FLQESNVLYQ HNLRRIKQFL QSRYLEKPME IARIVARCLW EESRLLQTAA TAAQQGGQAT HPTAAVVTEK QQMLEQHLQD VRKRVQDLEQ KMKVVENLQD DFDFNYKTLK SQGDMQDLNG NNQSVTRQKM QQLEQMLTAL DQMRRGIVSE LAGLLSAMEY VQKMLADEEL ADWKRRQQIA CIGGPPNICL DRLENWITSL AESQLQTRQQ IKKLEELQQK VSYKGDPIVQ HRPMLEERIV ELFRNLMKSA FVVERQPCMP MHPDRPLVIK TGVQFTTKVR LLVKFPELNY QLKIKVCIDK DSGDVAALRG SRKFNILGTN TKVMNMEESN NGSLSAEFKH LTLREQRCGN GGRANCDASL IVTEELHLIT FETEVYHQGL KIDLETHSLP VVVISNICQM PNAWASILWY NMLTNNPKNV NFFTKPPIGT WDQVAEVLSW QFSSTTKRGL SIEQLTTLAE KLLGPGVNYS GCQITWAKFC KENMAGKGFS FWVWLDNIID LVKKYILALW NEGYIMGFIS KERERAILST KPPGTFLLRF SESSKEGGIT FTWVEKDISG KTQIQSVEPY TKQQLNSMSF AEIIMGYKIM DATNILVSPL VYLYPDIPKE EAFGKYCRSE SQEHSEATDS GSAAPYLKTK FICVTPTSFS NTIDLPMSPR TLDSLMQFGN SSEGAEANAG GQFESLTFDM ELTQECASSP M
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
Protein Length
Partial
Tag Info
N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
Transcription factor that binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes.
Gene References into Functions
  1. Avian blood contains a leptin-like molecule that specifically binds to leptin receptor, suggesting that the leptin system is conserved across all vertebrate classes. PMID:24858374
  2. C3a induces retina regeneration via STAT3 activation, which activates the injury- and inflammation-responsive factors, IL-6, IL-8 and TNF-alpha and sets forth regulation of Wnt2b, Six3 and Sox2, genes associated with retina stem and progenitor cells. PMID:23942241
  3. STAT3 could play in the protection of cardiovascular function in a developing organism PMID:21279516

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Subcellular Location
Cytoplasm. Nucleus.
Protein Families
Transcription factor STAT family
Database Links

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