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Recombinant Chicken Pumilio homolog 1 (PUM1), partial

Recombinant Chicken Pumilio homolog 1 (PUM1), partial

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Target Background

Product Details

Abbreviation

PUM1

Purity

>85% (SDS-PAGE)

Target Names

PUM1

Uniprot NO.

Q2VB19

Alternative Names

PUM1; RCJMB04_1f11; Pumilio homolog 1

Species

Gallus gallus (Chicken)

Source

Yeast

Expression Region

1-1189

Target Protein Sequence

MSVACVLKRK AVLWQDSFSP HLKQHAQDTA NPNMPVVLTS GTGSQAQPQP AANQALAAGT HSSPVPGSIG VAGRSQDDAM VDYFFQRQHG EQLGGGGSGG GGYNNSKHRW PTGDNIHAEH QVRSMDELNH DFQALALEGR AMGEQLLPGK KFWESDDSSK DGPKGIFLGD QWRDSAWGTS DHSVSQPIMV QRRPGQGFHV NSEVNSVLSP RSESGGLGVS MVEYVLSSSP GDSCLRKGGF GPRDAENDEN DKGDKKNKGT FDGDKLGDLK EEGDVMDKTN GLPVQNGIDT DVKDFSRTPG NCQNSASEVD LLGPNQNGSE GLAQLASTNG AKPVEDFSNI ESQSVPLDPM EHVGMEPLQF DYSGTQVPVD SAAATVGLFD YNSQQQLFQR PNALAVQQLT AAQQQQYALA AAHQPHIAGL APAAFVPNPY IISAAPPGTD PYAAGLAAAA TLGPAVVPHQ YYGVTPWGVY PASLFQQQAA AAAAATNSAN QQTTQQTQQG QQQVLRGGAS QRPLTPNQNQ QGQQTDPLVA AAAVNSALAF GQGLAAGMPG YPVLAPAAYY DQTGALVVNA GARNGLGAPV RLVAPAPVII SSSAAQAAVA AAAASANGAA GGLAGTTNGP FRPLGTQQPQ PQPQQQPTNN LASSSFYGNN SLSSNSQSSS LFSQGSAQPA NTSLGFGSSS SLGATLGSAL GGFGTAVANS NTGSGSRRDS LTGSSDLYKR TSSSLTPIGH SFYNGLGFSS SPGPVGMPLP SQGPGHSQTP PPSLSSHGSS SSLNLGGLTN GSGRYISAAP GAEAKYRSAS SASSLFSPSS TLFPSSRLRY GMSDVMPSGR SRLLEDFRNN RYPNLQLREI AGHIMEFSQD QHGSRFIQLK LERATPAERQ LVFNEILQAA YQLMVDVFGN YVIQKFFEFG SLEQKLALAE RIRGHVLSLA LQMYGCRVIQ KALEFIPPDQ QVINEMVREL DGHVLKCVKD QNGNHVVQKC IECVQPQSLQ FIIDAFKGQV FALSTHPYGC RVIQRILEHC LPEQTLPILE ELHQHTEQLV QDQYGNYVIQ HVLEHGRPED KSKIVAEIRG NVLVLSQHKF ASNVVEKCVT HASRTERAML IDEVCTMNDG PHSALYTMMK DQYANYVVQK MIDVAEPAQR KIVMHKIRPH IATLRKYTYG KHILAKLEKY YMKNGVDLGP ICGPPNGII
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Sequence-specific RNA-binding protein that acts as a post-transcriptional repressor by binding the 3'-UTR of mRNA targets. Binds to an RNA consensus sequence, the Pumilio Response Element (PRE), 5'-UGUANAUA-3', that is related to the Nanos Response Element (NRE). Mediates post-transcriptional repression of transcripts via different mechanisms: acts via direct recruitment of the CCR4-POP2-NOT deadenylase leading to translational inhibition and mRNA degradation. Also mediates deadenylation-independent repression by promoting accessibility of miRNAs.

Subcellular Location

Cytoplasm. Cytoplasm, P-body. Cytoplasmic granule.

Tissue Specificity

Detected in embryonic male and female gonads, heart, liver and muscle. Detected in adult brain, testis, ovary, heart, lung, spleen, kidney and muscle.

Database Links

UNIGENE: Gga.22920

KEGG: gga:419554

STRING: 9031.ENSGALP00000000832

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