Recombinant Chicken Proto-oncogene c-Fos (FOS)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

FOS

Uniprot NO.

P11939

Alternative Names

FOSProto-oncogene c-Fos; Cellular oncogene fos

Species

Gallus gallus (Chicken)

Source

Yeast

Expression Region

1-367

Target Protein Sequence

MMYQGFAGEY EAPSSRCSSA SPAGDSLTYY PSPADSFSSM GSPVNSQDFC TDLAVSSANF VPTVTAISTS PDLQWLVQPT LISSVAPSQN RGHPYGVPAP APPAAYSRPA VLKAPGGRGQ SIGRRGKVEQ LSPEEEEKRR IRRERNKMAA AKCRNRRREL TDTLQAETDQ LEEEKSALQA EIANLLKEKE KLEFILAAHR PACKMPEELR FSEELAAATA LDLGAPSPAA AEEAFALPLM TEAPPAVPPK EPSGSGLELK AEPFDELLFS AGPREASRSV PDMDLPGASS FYASDWEPLG AGSGGELEPL CTPVVTCTPC PSTYTSTFVF TYPEADAFPS CAAAHRKGSS SNEPSSDSLS SPTLLAL
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. FOS has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. In growing cells, may activate phospholipid synthesis.

Gene References into Functions

Dimeric combinations of MafB, cFos and cJun in developing chick limb buds control the number of apoptotic cells. PMID:25005477
This study demonistereated that c-fos gene expression accompanying filial imprinting in the newly hatched chick brain. PMID:20170693
results suggest that the learning-related increase in Fos protein production, which occurs in identifiable neuronal sub-populations in the intermediate and medial mesopallium, reflects events that make an early contribution to learning and/or memory PMID:19756549
The expression of c-fos in the optokinetic nuclei is linked to near peak firing rates and the novelty and duration of the visual signals, supporting the assumption that expression is related to stimulus contexts leading to neuronal plastic changes. PMID:19217933