Recombinant Chicken Prostaglandin G/H synthase 2 (PTGS2), partial

Product Details

Purity
>85% (SDS-PAGE)
Target Names
PTGS2
Uniprot NO.
Species
Gallus gallus (Chicken)
Source
Yeast
Expression Region
18-603
Target Protein Sequence
ANP CCSLPCQNRG VCMTTGFDRY ECDCTRTGYY GENCTTPEFF TWLKLILKPT PNTVHYILTH FKGVWNIINN ISFLRDTIMR YVLTSRSHLI DSPPTYNSDY SYKSWEAYSN LSYYTRSLPP VGHDCPTPMG VKGKKELPDS KLIVEKFLLR RKFIPDPQGT NVMFTFFAQH FTHQFFKTDH KKGPGFTKAY GHGVDLNHIY GETLERQLKL RLRKDGKLKY QMIDGEMYPP TVKDTQAEMI YPPHVPEHLQ FSVGQEVFGL VPGLMMYATI WLREHNRVCD VLKQEHPEWD DEQLFQTTRL ILIGETIKIV IEDYVQHLSG YHFKLKFDPE LLFNQRFQYQ NRIAAEFNTL YHWHPLLPDT FQIHNQEYTF QQFLYNNSIM LEHGLSHMVK SFSKQSAGRV AGGKNVPAAV QKVAKASIDQ SRQMRYQSLN EYRKRFMLKP FKSFEELTGE KEMAAELEEL YGDIDAMELY PGLLVEKPRP GAIFGETMVE IGAPFSLKGL MGNTICSPEY WKPSTFGGKV GFEIINTASL QKLICNNVKG CPFTAFHVLN PEPTEATINV STSNTAMEDI NPTLLLKEQS AEL
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
Protein Length
Partial
Tag Info
N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage
Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays important roles in modulating motility, proliferation and resistance to apoptosis.
Gene References into Functions
  1. COX-2 mRNA expression did not change as a function of age or in ovarian cancer PMID:18498063

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Subcellular Location
Microsome membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein.
Protein Families
Prostaglandin G/H synthase family
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
No. 269, Shendun 5th Road, Donghu Hi-Tech Development Area, Hubei Province, 430206, P.R.China
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