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Recombinant Chicken Prospero homeobox protein 1 (PROX1), partial

Recombinant Chicken Prospero homeobox protein 1 (PROX1), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

PROX1

Purity

>85% (SDS-PAGE)

Target Names

PROX1

Uniprot NO.

Q91018

Species

Gallus gallus (Chicken)

Source

Yeast

Expression Region

1-736

Target Protein Sequence

MPDHDSTALL SRQTKRRRVD IGVKRTVGTA SAFFAKARAT FFSAMNPQGS EQDVEYSVVQ HADGEKPNVL RKLLKRANSY EDAMMPFPGA TIISQLLKNN MNKNGGTEPS FQASGLSSTG SEVHQEDVCS NSSRDSPQEC LSPFGRPTMS QFDVDRLCDE HLRAKRARVE NIIRGMSHSP RVALRGNENE REIRPQSVSP RESYRENKRK QNWPQQQQQS FQQLVSARKE QKREERRQLK QQLEDMQKQL RQLQEEFYQI YDSTDSENDE DGNLSEDRMR SETVDAQAGD SVGRSDNEMC ELDPGQFIDR ARALIREQEI GENKPKREGP KEKDQGPNSF HPEGKHLAET LKQELNTAMS QVVDTVVKVF SSKPSRQLPQ VFPPLQIPQA RFAVNGENHN FHTANQRLQC FGDVIIPNPL DTFSSVPMPG ATDQTDALPL VVRKNSSDQP ASAPPAGGHH ASLHQSPLSA TAGFSTSSFR HPFPLPLMAY PFQSPLGAPS ASFPGKERAS PESLDLTRET TSLRTKMSSH HMNHHPCSPA HPPSAAEGLS LSLIKSECGD LQDMSEISPY SGSAMQEGLS PNHLKKAKLM FFYTRYPSSN MLKTYFSDVK FNRCITSQLI KWFSNFREFY YIQMEKYARQ AINDGVTSTE ELSITRDCEL YRALNMHYNK ANDFEVPERF LEVAQITLRE FFNAIIAGKD VDPSWKKAIY KVICKLDSEV PEIFKSPNCL QELLHE
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Transcription factor which may be involved in developmental processes such as cell fate determination, gene transcriptional regulation and progenitor cell regulation in a number of organs. May be essential in the development and function of the eye. May play a role in the regulation of the circadian rhythm by repressing the expression of clock genes.

Gene References into Functions

We show that b-catenin is expressed during the pre-patterning of the epithelium prior to papilla induction and second that b-catenin, Ednrb and Inhba are expressed during the induction and patterning of the conjunctival papillae. Furthermore, we identified two genes, b-catenin and Prox1, that may be involved in the induction of the underlying scleral bones PMID:27664768
Results define the neurogenesis period in the chick paravertebral sympathetic ganglia including an initial cell cycle withdrawal and identify Prox1 as a marker and regulator of proliferating sympathetic neuroblasts PMID:25788138
Results showed that VEGF-A/HGF combination was able to induce a strong angiogenic response and the expression of Prox-1 in the lymphatic endothelial cells of the chick embryo chorioallantoic membrane. PMID:20033752
Data show that Prox1 is expressed in embryonic sympathetic trunk ganglia of avian and murine embryos. PMID:20453716
These data suggest that Prox1 function as a transcriptional activator could be regulated at the DNA level based on the characteristics of the responsive elements. PMID:18385074