Recombinant Chicken Osteopontin (SPP1)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
Have Questions?	Leave a Message or Start an on-line Chat

Product Details
Related Products
Customer Reviews and Q&A
Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

SPP1

Uniprot NO.

P23498

Species

Gallus gallus (Chicken)

Source

Yeast

Expression Region

17-264

Target Protein Sequence

WPVS KSRQHAISAS SEEKYDPRSH HTHRYHQDHV DSQSQEHLQQ TQNDLASLQQ THYSSEENAD VPEQPDFPDI PSKSQEAVDD DDDDDNDSND TDESDEVVTD FPTEAPVTPF NRGDNAGRGD SVAYGFRAKA HVVKASKLRK AARKLIEDDA TAEVGDSQLA GLWLPKESRE QDSRELAQHQ SVENDSRPRF DSPEVGGGDS KASAGVDSRE SLASRSAVDT SNQTLESAED AEDRHSIENN EVTR
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

■ Customer Reviews

Submit a Review here

Target Background

Function(From Uniprot)

Major non-collagenous bone protein that binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction.; Acts as a cytokine involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10 and is essential in the pathway that leads to type I immunity.

Gene References into Functions

results of this study indicate that SPP1 is novel in that its expression is down-regulated by estrogen in epithelial cells of the chicken oviduct and that it is up-regulated in chicken ovarian endometrioid tumor that could be used for monitoring effects of therapies for this disease in laying hens. PMID:22588173
fibroblast growth factor signaling directly activates osteopontin expression independent of chondrocytes differentiation PMID:16253490
Polymorphisms within the osteopontin gene (SPP1) are associated with 5-week body weight. PMID:16734694
OPN inhibited calcite growth in vitro at the crystallographic faces producing altered crystal morphology and circular growth step topography PMID:18511297
Matrix-mineral relationships in the eggshell at the ultrastructural level were studied using scanning and transmission electron microscopy, and the distribution of osteopontin is described. PMID:18698131
The effects of osteopontin and calbindin synthesis in the eggshell gland on the quality of egg shells in laying hens are reported. PMID:19211537