Recombinant Chicken Optineurin (OPTN), partial

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

OPTN

Purity

>85% (SDS-PAGE)

Target Names

OPTN

Uniprot NO.

Q90Z16

Species

Gallus gallus (Chicken)

Source

Yeast

Expression Region

1-556

Target Protein Sequence

MSSKPQIRPA ENGEHCRSKM ENGMDSMAPP TLSTYTPEEM VQQMKELITE NNELKEAMKL HNQAMKDRYE ELSIWREKQK EEREFYETKF KEAKQCLLAK CVENEQLQQQ LQSLKEREEG AEMEGCATPE KEARQLKSKV QRLQAEKADL LAIISELQVK LNIASAEDSF VEIGMNEEVN RTARENQDNS SEMASNIAVY IRSKSADESK NLESEELTVS QLLCCLRNET QRREKLEKEL QDHKERLSKM ENETSNCLES GTQTNQEEES SEAIGSEVES LKKQICALFK ELQEAHEKLK EAELIQKKLQ EKCQTLEKVN SAAATELEEK QQLIYTIKKL ELQVESVQAE VKLEQAKTQD EKTRYSSLQD AYNKLLAELT EAMKTISEMK VKEHDRVDKV VVEELNAKVL LAEQALAAKQ LQMDEMKQLI AKQEEDLETM AVLRAQMEVY CSDFHAERAA REKIHEEKEQ LAVQLAYLLK EQQNLEDLGR SSLAEMQNRH GARAPDREHS PRLVQRGTGS QEWPEQRNIS IYSCPKCEEI LPDLDTLQIH VMDCIN
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Probably part of the TNF-alpha signaling pathway that can shift the equilibrium toward induction of cell death. May act by regulating membrane trafficking and cellular morphogenesis. May act as autophagy receptor that interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family.

Subcellular Location

Cytoplasm. Cytoplasm, perinuclear region. Golgi apparatus. Golgi apparatus, trans-Golgi network. Cytoplasmic vesicle. Recycling endosome. Cytoplasmic vesicle, autophagosome.

Tissue Specificity

Expressed in erythrocytes, skeletal muscle, heart, spleen and brain. Weakly expressed in lung and liver (at protein level).

Database Links

UNIGENE: Gga.4189

KEGG: gga:374079

STRING: 9031.ENSGALP00000022287

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