Recombinant Chicken Nucleophosmin (NPM1)

Product Details

Purity
>85% (SDS-PAGE)
Target Names
NPM1
Uniprot NO.
Alternative Names
NPM1; Nucleophosmin; NPM; Nucleolar phosphoprotein B23; Nucleolar protein NO38; Numatrin
Species
Gallus gallus (Chicken)
Source
Yeast
Expression Region
1-294
Target Protein Sequence
MEDSAMDMES MGPLRPQTFL FGCELKAEKE YQFKVDDEEN EHQLSLRTVT LGAGAKDELH VVEAEALDYE GNPTKVVLAS LKMSVQPTVS LGGFEITPPF VLRLKCGSGP VYVSGQHLVA LEEEPESEDE EEDTKIGNAS TKRPASGGGA KTPQKKPKLS EDDEDDDEDE DDDEDDEDDL DDDEEEIKTP MKKPAREPAG KNMQKAKQNG KDSKPSTPAS KTKTPDSKKD KSLTPKTPKV PLSLEEIKAK MQASVDKGCS LPKLEPKFAN YVKNCFRTED QKVIQALWQW RQTL
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
Protein Length
Full length protein
Tag Info
N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage Condition
Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
Acts as a chaperonin for the core histones H3, H2B and H4. Associated with nucleolar ribonucleoprotein structures and bind single-stranded nucleic acids. It may function in the assembly and/or transport of ribosome. May stimulate endonuclease activity on apurinic/apyrimidinic (AP) double-stranded DNA. May inhibit endonuclease activity on AP single-stranded RNA.
Gene References into Functions
  1. Phosphoprotein B23 targets Newcastle disease virus matrix protein to the nucleoli and facilitates viral replication. PMID:24606698
  2. Matrix protein of Newcastle disease virus interacts with chicken nucleophosmin B23.1. PMID:24195380

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Subcellular Location
Cytoplasm. Nucleus, nucleoplasm. Nucleus, nucleolus.
Protein Families
Nucleoplasmin family
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
No. 269, Shendun 5th Road, Donghu Hi-Tech Development Area, Hubei Province, 430206, P.R.China
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