Recombinant Chicken Nuclear factor NF-kappa-B p105 subunit (NFKB1), partial

Product Details

Purity
>85% (SDS-PAGE)
Target Names
NFKB1
Uniprot NO.
Alternative Names
NFKB1; Nuclear factor NF-kappa-B p105 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit]
Species
Gallus gallus (Chicken)
Source
Yeast
Expression Region
1-983
Target Protein Sequence
MAGEDPYIMG VSDPQMFAMD QLMGMSTIFN NTGYITSDLP LRTADGPYLQ IIEQPKQRGF RFRYVCEGPS HGGLPGASSE KNKKSYPQVK ICNYVGPAKV IVQLVTNGKY VHLHAHSLVG KFCEDGVCTV NAGPKDMVVG FANLGILHVT KKKVFETLET RMIDACKKGY NPGLLVHPEL GYLQAEGCGD RQLTEREREI IRQAAVQQTK EMDLSVVRLM FTAFLPDSNG GFTRRLDPVI SDAIYDSKAP NASNLKIVRM DRTAGCVTGG EEIYLLCDKV QKDDIQIRFY EEDENGGMWE GFGDFSPTDV HRQFAIVFKT PKYRDVNITK PASVFVQLRR KSDLETSEPK PFLYYPEIKD KEEVQRKRQK LMPNFSDGYG GGSGAGGGGM FGGGGGGAGS GFSYPSYGYS AFGGMHFHPG TTKSNAGMKH ELSNSTVKKD EESSDKQSDK WDTKHDVKVE TVEKNECRTS GHNEEKEDAS LCCKDEGNKP KCGCQDGLFL EKAMQLAKRH CNALFDYAVT GDVRMLLAVQ RHLTAVQDDN GDNVLHLSII HLHRELVKNL LEVMPDMNYN NIINMRNDLY QTPLHLAVIT KQAEVVEDLL KAGANVNLLD RHGNSVLHLA AAEGDDKILS LLLKHQKASS MIDLSNGEGL SAIHMVVTAN SLSCLKLLIA AGVDVNAQEQ KSGRTALHLA VEQENVPLAG CLLLEGDADV DSTTYDGTTP LHIAAGRGFT KLAAVLKAAG ADPHVENFEP LFDVEEDVKD DDDDEGIVPG TTPLDMAANW EVYDILNGKP YIAAAAVSED LLSQGPLREL NESSKQQLYK LLETPDPSKN WSTLAEKLGL GILNNAFRLS PSPSKTLLDN YKISGGTVQE LIAALTQMDH TEAIEVIQKA LSSSQRQSHQ EDNTIEAFPS LSPTSFAKEE TGELYNHKFQ DPESTCDSGV ETSFRKLSFT YSDSLNSKSS ITLSKMTLGY RKAQCKAVIY LTR
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
Protein Length
Partial
Tag Info
N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage Condition
Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)
P105 is the precursor of the p50 subunit of the nuclear factor NF-kappa-B, which binds to the kappa-B consensus sequence 5'-GGRNNYYCC-3', located in the enhancer region of genes involved in immune response and acute phase reactions. The precursor protein itself does not bind to DNA.
Gene References into Functions
  1. EGF stimulated proliferation of chicken PGCs via activation of Ca(2+)/PKC involving NFKB1 signaling pathway. PMID:19005168

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Subcellular Location
Nucleus. Cytoplasm. Note=Nuclear, but also found in the cytoplasm in an inactive form complexed to an inhibitor (I-kappa-B).
Database Links

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