Recombinant Chicken NF-kappa-B inhibitor alpha (NFKBIA)

Product Details

Abbreviation
NFKBIA
Purity
>85% (SDS-PAGE)
Target Names
NFKBIA
Uniprot NO.
Alternative Names
NFKBIA; IKBANF-kappa-B inhibitor alpha; I-kappa-B-alpha; IkB-alpha; IkappaBalpha; REL-associated protein pp40
Species
Gallus gallus (Chicken)
Source
Yeast
Expression Region
1-318
Target Protein Sequence
MLSAHRPAEP PAVEGCEPPR KERQGGLLPP DDRHDSGLDS MKEEEYRQLV RELEDIRLQP REPPARPHAW AQQLTEDGDT FLHLAIIHEE KALSLEVIRQ AAGDAAFLNF QNNLSQTPLH LAVITDQAEI AEHLLKAGCD LDVRDFRGNT PLHIACQQGS LRSVSVLTQH CQPHHLLAVL QATNYNGHTC LHLASIQGYL AVVEYLLSLG ADVNAQEPCN GRTALHLAVD LQNSDLVSLL VKHGPDVNKV TYQGYSPYQL TWGRDNASIQ EQLKLLTTAD LQILPESEDE ESSESEPEFT EDELMYDDCC IGGRQLTF
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
Protein Length
full length protein
Tag Info
N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage Condition
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. May be involved in regulation of transcriptional responses to NF-kappa-B, including cell adhesion, immune and proinflammatory responses, apoptosis, differentiation and growth. Controlled by sequential serine-phosphorylation, ubiquitination and degradation. Tyrosine-phosphorylation could only lead to dissociation from NF-kappa-B.
Subcellular Location
Cytoplasm.
Protein Families
NF-kappa-B inhibitor family
Tissue Specificity
Highly expressed in lymph node, thymus followed by liver, brain, muscle, kidney, gastrointestinal and reproductive tract.
Database Links

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