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Recombinant Chicken Myeloid differentiation primary response protein MyD88 (MYD88)

Recombinant Chicken Myeloid differentiation primary response protein MyD88 (MYD88)

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

MYD88

Uniprot NO.

A5HNF6

Alternative Names

MYD88; RCJMB04_14h3; Myeloid differentiation primary response protein MyD88

Species

Gallus gallus (Chicken)

Source

Yeast

Expression Region

1-299

Target Protein Sequence

MATVPVGAGS APGPEPADLH SVPMVALNYG VRRRLGLYLN PRAATAADWT ALAEKLGHDY LEIRRLEALP DPTAALLEEW QSRCPGGATV GQLLELLRQL GRHDVLLELG GSVEEDCKKY LRRKQQEAEQ PLQVPAVDSS VPKTSELMGI TTRDDPYGHG TEMFDAFICY CQKDLQFVQE MIRELEQTEF KLKLCVFDRD VLPGTCVWSI SGELIERRCR RMVVVISDDY LESDECDFQT KFALSLSPGA RLKRLIPVKC KTMKNEFPSI LRFITICDYT NPCTKKWFWT RLAKSLLLP
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.

Gene References into Functions

The results demonstrated that ChTLR4, ChTLR15 and MyD88 were involved in E. tenella sporozoites recognition and subsequent signal transduction. PMID:23352867
MyD88 gene expression was detected in each tissue tested except in muscle. PMID:17676477
Over-expression of chicken isoform 2 significantly induces activation of NF-kappaB in vitro; chicken MyD88-2 may play an important role in chicken innate immune responses. PMID:18582498

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Subcellular Location

Cytoplasm. Nucleus. Note=Predominantly cytoplasmic, with some expression in the nucleus.

Tissue Specificity

Expressed in spleen, liver, kidney, bursa of Fabricius, lung and brain (at protein level). Expressed in cecum, heart, spleen, liver, kidney, female reproductive tract, thymus, bursa of Fabricius, muscle and lung.

Database Links

UNIGENE: Gga.17397

KEGG: gga:420420

STRING: 9031.ENSGALP00000009551

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