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Recombinant Chicken Melanocyte protein PMEL (PMEL), partial

Recombinant Chicken Melanocyte protein PMEL (PMEL), partial

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

PMEL

Purity

>85% (SDS-PAGE)

Target Names

PMEL

Uniprot NO.

Q98917

Species

Gallus gallus (Chicken)

Source

Yeast

Expression Region

20-763

Target Protein Sequence

Q QRGGGRSRGG VKGSAWGGRP APFRSWDTAR YRPWQEGTAR QNDCWRGGDV TFDISNDAPT LVGARATFSI ALRFPGTQTV LPDGRVVWSQ NCTVNGTRML QGDPVYPEQL AEGSDGVFPD GQPFPRSAWG KRGRFVYVWW TWGRYWQVVD GATSQLTVGT DGVALGSYTM EVVVYHYRGR QRFIPIGHAS TQFSITDQVP IAVDVTQLEV AAGDGGSFVR NRPVAFNVRL HDPSHYLRDA DISYSWDFGD QSGTLISRSP TVTHTYLQAG SFAARLVLQA AIPLSSCGTS APPVVDPTTG PVPSLGPTAT QPVGPTGSGT ATAPSNLTGS GTAAAPGTTA APRASGAPAE PTGVSVAVLS DSAATEPLPD PVLSTAVADA AAGTDPTADP LPPTSVSSGG DAPGTVAPTA VEGSVAAGVG TAEDVAAATP GATAADVAVD TAGATDGDAV GPTAAATAES IADPTAGATD GDAVGATAES IADPTAGATD GDAVGPTAAA TAESIADPTA GATAVSSGSA TAGATAEPLL LVKRQAPEAE PTGCVLYRYG TFSTELNIVQ GIESVAIVQV VPAAPEGSGN SVELTVTCEG SLPEEVCTVV ADAECRTAQM QTCSAVAPAP GCQLVLRQDF NQSGLYCLNV SLANGNGLAV ASTHVAVGGA SPAASGTTLT VGLLWAPLIA AALGTAAYTY RRVKYSPLLP TAPTAPRPHS WLPPGATLRL LLRQAFGGAP SGESSPLLRA NAV
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

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Target Background

Function(From Uniprot)

Might be required for polymerization of melanin onto the core structure of melanosomes with enzymatic function of tyrosinase.

Gene References into Functions

The study strongly suggests a correlated effect between plumage colour and behaviour, and we conclude that PMEL17 may have a pleiotropic effect on social and explorative behaviour in chickens. PMID:20461577
the transmembrane region may contribute to the structural integrity of Silver/Pmel17 oligomers or influence toxic, amyloidogenic properties PMID:19679373
Dominant white is exclusively associated with a 9-bp insertion in exon 10, Dun is associated with a deletion of 15-bp in exon 10, and Smoky has the same 9-bp insertion as Dominant white as well as a 12-bp deletion in exon 6 of PMEL17. PMID:15579702
Genotype of PMEL17 affects plumage color and feather pecking behavior. PMID:17106652
In addition to the 9-bp insertion, WLs and KOCs have unique bases in single nucleotide polymorphisms (SNPs) at the 1,777th and 3,118th bases in the PMEL17 gene. PMID:17436332
Dominant white mutation does not cause visual impairment PMID:19751488