Recombinant Chicken Leptin (LEP)

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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

LEP

Uniprot NO.

O42164

Species

Gallus gallus (Chicken)

Source

Yeast

Expression Region

19-163

Target Protein Sequence

VP CQIFQDDTKT LIKTIVTRIN DISHTSVSAK QRVTGLDFIP GLHPILSLSK MDQTLAVYQQ VLTSLPSQNV LQIANDLENL RDLLHLLAFS KSCSLPQTSG LQKPESLDGV LEASLYSTEV VALSRLQGSL QDILQQLDIS PEC

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free

Storage

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Description

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Target Background

Function

Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways.

Subcellular Location

Secreted.

Protein Families

Leptin family

Tissue Specificity

Not exclusively localized in adipose tissue but is also expressed in liver.

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