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Recombinant Chicken Inhibitor of nuclear factor kappa-B kinase subunit alpha (CHUK), partial

Recombinant Chicken Inhibitor of nuclear factor kappa-B kinase subunit alpha (CHUK), partial

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Target Background

Product Details

Abbreviation

CHUK

Purity

>85% (SDS-PAGE)

Target Names

CHUK

Uniprot NO.

Q5ZJB4

Alternative Names

CHUK; IKKA; RCJMB04_19h23Inhibitor of nuclear factor kappa-B kinase subunit alpha; I kappa-B kinase alpha; IKK-A; IKK-alpha; IkBKA; IkappaB kinase; EC 2.7.11.10; Conserved helix-loop-helix ubiquitous kinase; Nuclear factor NF-kappa-B inhibitor kinase alpha; NFKBIKA

Species

Gallus gallus (Chicken)

Source

Yeast

Expression Region

1-759

Target Protein Sequence

MERGAERGPP PAPGGVALRG QPAGGCGPWE MRDRLGTGGF GNVCLYQHQD TGARVAIKSC RLELSVKNKD RWCHEIDIMK KLNHPNVVRA CEVPEEMNFL VNDVPLLAME YCSGGDLRKL LNKPENCCGL KESQILSLLS DIGSGIQYLH ENRIIHRDLK PENIVLQDEG GKIIHKIIDL GYAKDLDQGS LCTSFVGTLQ YLAPELFENK SYSVTVDYWS FGTMVFECIA GFRPFLHNLQ PFTWHEKIKK KDPKHIFASE EMNGEVRFST HLPQPHSICS LIVEPMESWL QLMLNWDPEQ RGGGLDPETN SPKCFLLMDH ILNLKIVHIL NMTSAKIVSF LLHPEESLHF LQNRIESETG ISTGNQELLL ETGICLDPRK PASQCVIDGV RGWDSYMVYL FDKSKTVYDG PFASRSLSEC VNYIVQDSKI QLPIPQLRKV WAEAVHYVIG LKEDYSRLFQ GQRAAMLSLL RYNANLIKMK NNMVSASQQL KAKLEFFHQS IRLDLERYSD QMAYGISSEK MLKAWKEMEE KASHCAQAED IGYLDEQIMA LHTEIVELQK SPYARRQGEV MESLEQRAID LYKQLKTRPP DHAYSDSTDM VKIIVQTVQS QDRVLKELFG HLSKLLGCKQ KIIDLLPKIE VALNNIKEAD NSEMQMQGKR QREIWHLLKI ACTQSSSRSL VSSSLEGTAS TPAATWVPQS SSEYAPHPLS SMATPGDGEN FVDVIEENLN YLDRFSSMLQ EAREEQNNSL TNFDWSWLK
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

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Target Background

Function(From Uniprot)

Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines.

Subcellular Location

Cytoplasm. Nucleus.

Protein Families

Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily

Database Links

UNIGENE: Gga.5483

KEGG: gga:423669

STRING: 9031.ENSGALP00000005196

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