Recombinant Chicken GATA-binding factor 3 (GATA3)

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

GATA3

Uniprot NO.

P23825

Alternative Names

GATA3; GATA-binding factor 3; GATA-3; Transcription factor NF-E1c

Species

Gallus gallus (Chicken)

Source

Yeast

Expression Region

1-444

Target Protein Sequence

MEVSTDQPRW VSHHHPAVLN GQHPDSHHPT LGHTYMDPTQ YPLAEEVDVL FNIDGQGNPV PPYYGNSVRA TVQRYPTAHH GSQVCRPPLL HGSLPWLDGS KALSSHHSAS PWNLSPFSKT SIHHSSPGPL SVYPPASSST LSAGHSSPHL FTFPPTPPKD VSPDPSISTP GSTGSTRQDE KECIKYQVSL ADTMKLESSH SRSSMASLGG ATSSAHHPIT TYPPYVPEYS SGLFPPSSLL GGSPTGFGCK SRPKARSSTE GRECVNCGAT STPLWRRDGT GHYLCNACGL YHKMNGQNRP LIKPKRRLSA ARRAGTSCAN CQTTTTTLWR RNANGDPVCN ACGLYYKLHN INRPLTMKKE GIQTRNRKMS SKSKKCKKVH DNLEDFPKSS SFNPAALSRH MSSISHISPF SHSSHMLTTP TPMHPPSSLS FGPHHPSSMV TAMG
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Transcriptional activator which probably serves as a general switch factor for cell-specific development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of genes.

Gene References into Functions

data establish Gata2 and Gata3 as essential members of the transcription factor network controlling sympathetic neuron development. PMID:15329349
GATA3 impacts WNT signaling in this region of the sensory macula. PMID:19924793
Gata3 was mainly expressed in the developing sensory epithelia, reflecting the importance of this factor in the sensory-neural development of the inner ear. PMID:17103399
During regeneration in the avian utricle, regionalized expression of GATA3 is maintained after severe hair cell lesions and after transplantation of the sensory epithelium onto a chemically defined substrate. PMID:17154269
Our results suggest that Gata3 may be specifically involved in the differentiation of auditory ganglion neurons during embryogenesis. PMID:19673002