Recombinant Chicken GATA-binding factor 2 (GATA2)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

GATA2

Uniprot NO.

P23824

Species

Gallus gallus (Chicken)

Source

Yeast

Expression Region

1-466

Target Protein Sequence

MEVATDQPRW MTHHAVLNGQ HPESHHPGLA HNYMEPAQLL PPDEVDVFFN HLDSQGNPYY ANSAHARARV SYSQAHARLT GSQMCRPHLI HSPGIPWLDS SKAALSAHHH NPWTVNPFTK TPLHPSAAGA PGAISVYPGS STSSTASVSS LTPASHSGSH LFGFPPTPPK EVSPDPNSTS AASPSSSAGA RQEDKDSIKY QVSLSEGMKM ESASPLRSSL TSMGAQPSTH HPIPTYPSYV PAAHDYSSSL FHPGSFLGGP ASSFTPKPRS KARSCSEGRE CVNCGATATP LWRRDGTGHY LCNACGLYHK MNGQNRPLIK PKRRLSAARR AGTCCANCQT TTTTLWRRNA NGDPVCNACG LYYKLHNVNR PLTMKKEGIQ TRNRKMSNKS KKSKKGSECF EELSKCMQEK SSPFSAAALA SHMAPMGHLP PFSHSGHILP TPTPIHPSSS ISFGHPHPSS MVTAMG
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Transcriptional activator which probably serves as a general switch factor for cell-specific development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of genes.

Gene References into Functions

Results provide new insights into the selective roles of Gata2 within the genetic model of V2 interneurons development and in particular on the hierarchy between V2-transcription factors PMID:25369423
Gata2 influences the site of primitive streak formation and its role is independent from, and upstream of, Vg1 and Wnt PMID:23093427
Within the rostral hindbrain, the Shh-activated homeodomain proteins Nkx2.2 and Nkx6.1 cooperate to induce the closely related zinc-finger transcription factors Gata2 and Gata3. (Gata2) PMID:14973276
data establish Gata2 and Gata3 as essential members of the transcription factor network controlling sympathetic neuron development PMID:15329349
At later stages, Gata2 expression became prominent in vestibular and cochlear nonsensory epithelia PMID:17103399