Recombinant Chicken Estrogen receptor beta (ESR2)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Target Background

Product Details

Abbreviation

ESR2

Purity

>85% (SDS-PAGE)

Target Names

ESR2

Uniprot NO.

Q9PTU5

Alternative Names

ESR2; NR3A2Estrogen receptor beta; ER-beta; cERb; Nuclear receptor subfamily 3 group A member 2

Species

Gallus gallus (Chicken)

Source

Yeast

Expression Region

1-472

Target Protein Sequence

MAFCSPAMLN YNIASNFGDS ESASVRQTSS PSVLWSAPGH LSPLTLHCQS SLLYAEQPKS PWCEVRPLDP VLPVTRETLK RKTNGSDCTS PIASNPGSKR DAHFCAVCSD YASGYHYGVW SCEGCKAFFK RSIQGHNDYI CPATNQCTID KNRRKSCQAC RLRKCYEVGM MKCGSRRERC GYRILRRHRN SEDCMGKTKK YNEAATRVKE ILLSTVSPEQ FVLTLLEAEP PNVLVSRPSK PFTEASMMMS LTKLADKELV HMIGWAKKIP GFIDLSLYDQ VRLLESCWME VLMIGLMWRS IDHPGKLIFA PDLVLDRDEG KCVEGILEIF DMLLAMTSRF RELKLQHKEY LCVKAMILLN SSMFPLSPEE PESNRKLHHL LNVVTDALVW VIAKSGIPSQ QQTTRLANLL MLLSHVRHAS NKGMEHLLSM KCKNVVPVYD LLLEMLNAHT LRGQRKSPVT HPEFEQVSHF QV
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Binds estrogens with an affinity similar to that of ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner.

Gene References into Functions

The expression of cathepsin E-A-like was regulated by oestrogen, and the regulative effect was predominantly mediated through ER-Beta in liver of chicken. PMID:29666334
Changes in ERbeta level suggest that this form of estrogen receptor plays a predominant role for estrogen action in the chicken adrenal gland during stress. PMID:23342917
Results describe the efects of daidzein, alone or in combination with estrogen, on estrogen receptor alpha and/or beta-mediated transactivation and on chicken hepatic vitellogenin II expression. PMID:20043933

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Subcellular Location

Nucleus.

Protein Families

Nuclear hormone receptor family, NR3 subfamily

Database Links

UNIGENE: Gga.314

KEGG: gga:395575

STRING: 9031.ENSGALP00000019234

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