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Recombinant Chicken Estrogen receptor (ESR1), partial

Recombinant Chicken Estrogen receptor (ESR1), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

ESR1

Uniprot NO.

P06212

Alternative Names

ESR1; ESR; NR3A1Estrogen receptor; ER; ER-alpha; Estradiol receptor; Nuclear receptor subfamily 3 group A member 1

Species

Gallus gallus (Chicken)

Source

Yeast

Expression Region

1-589

Target Protein Sequence

MTMTLHTKAS GVTLLHQIQG TELETLSRPQ LKIPLERSLS DMYVESNKTG VFNYPEGATY DFGTTAPVYG STTLSYAPTS ESFGSSSLAG FHSLNNVPPS PVVFLQTAPQ LSPFIHHHSQ QVPYYLENEQ GSFGMREAAP PAFYRPSSDN RRHSIRERMS STNEKGSLSM ESTKETRYCA VCNDYASGYH YGVWSCEGCK AFFKRSIQGH NDYMCPATNQ CTIDKNRRKS CQACRLRKCY EVGMMKGGIR KDRRGGEMMK QKRQREEQDS RNGEASSTEL RAPTLWTSPL VVKHNKKNSP ALSLTAEQMV SALLEAEPPI VYSEYDPNRP FNEASMMTLL TNLADRELVH MINWAKRVPG FVDLTLHDQV HLLECAWLEI LMIGLVWRSM EHPGKLLFAP NLLLDRNQGK CVEGMVEIFD MLLATAARFR MMNLQGEEFV CLKSIILLNS GVYTFLSSTL KSLEERDYIH RVLDKITDTL IHLMAKSGLS LQQQHRRLAQ LLLILSHIRH MSNKGMEHLY NMKCKNVVPL YDLLLEMLDA HRLHAPAARS AAPMEEENRN QLTTAPASSH SLQSFYINSK EEESMQNTI
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.

Gene References into Functions

The variations of ESR1 or PR expression or dominance of either PR expression is differentially regulated depending on the cell type in the chicken oviduct. PMID:26519127
differential expression of ER-alpha in both chicken ovaries during development in a cell type-specific distribution, suggesting that these differences may be regarded as an important cause in the process of asymmetric ovarian development in the chicken PMID:24704443
There were no significant differences in ERalpha mRNA expression during stress induced by fasting and refeeding. PMID:23342917
cell-specific distribution of ERalpha and AR in the anterior pituitary from adult cockerels by immunohistochemistry PMID:22453555
Data show that estrogen receptor 1 mRNA is over-expressed in early-stage tumors, suggesting that expression of the oviduct-related genes may be regulated by estrogen. PMID:21761365
ERalpha plays an important role in sex differentiation of the reproductive tract in female chicken embryos and can mediate xenoestrogen-induced disturbances of sex differentiation. PMID:21420409
immunohistochemical (IHC) localization of oestrogen receptor alpha was studied in the developing left ovary of 14.5-day-old chick embryos; intracellular localization was cytoplasmic, nuclear, or both PMID:20887390
Down-regulation of DMRT1 and up-regulation of ER alpha in rooster testes treated with exogenous pEGFP-N1-chicken male hypemethylated (cMHM) plasmid might indicate a novel cMHM non-coding RNA-mediated mechanism in avian sex differentiation. PMID:19597752
Content of estrogen receptor-alpha (ER-alpha) isoforms related to degree of brain development in chicks (Estrogen receptor alpha) PMID:14511763
ERalpha is localized in the nucleus of all cell subpopulations of the left ovary and only in epithelial cells of the lacunar channels of the right ovary. PMID:15704009
The ontogeny of ESR1 and its co-localization with pituitary hormones in the chick pituitary was studied. PMID:15789219