Recombinant Chicken Calbindin (CALB1)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

CALB1

Uniprot NO.

P04354

Alternative Names

CALB1Calbindin; Calbindin D28; D-28K; Vitamin D-dependent calcium-binding protein; avian-type

Species

Gallus gallus (Chicken)

Source

Yeast

Expression Region

2-262

Target Protein Sequence

TAETHLQGV EISAAQFFEI WHHYDSDGNG YMDGKELQNF IQELQQARKK AGLDLTPEMK AFVDQYGKAT DGKIGIVELA QVLPTEENFL LFFRCQQLKS SEDFMQTWRK YDSDHSGFID SEELKSFLKD LLQKANKQIE DSKLTEYTEI MLRMFDANND GKLELTELAR LLPVQENFLI KFQGVKMCAK EFNKAFEMYD QDGNGYIDEN ELDALLKDLC EKNKKELDIN NLATYKKSIM ALSDGGKLYR AELALILCAE EN
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3',5'-cyclic nucleotide phosphodiesterase.

Gene References into Functions

The vector-based transient receptor potential vanilloid 6(TRPV6)-shRNA can efficiently suppress the mRNA and protein expression of TRPV6 in chicken osteoblasts, and TRPV6 regulates the expression of calbindin-D28K during Ca2+ transport. PMID:25681476
increase of transient receptor potential cation channel subfamily V member 6 (TRPV6) and calbindin-D28k expression during eggshell formation suggests that active Calcium(2+) transport exerts effects in delivering active calcium in egg shell gland PMID:23796121
Calbindin-D28k has significant roles in neuroplasticity of the retina during postnatal development, when it is stimulated with different light conditions. PMID:23447106
This study concluded that calbindin-D28k localization in intestinal segments and eggshell gland is negatively affected by high ambient temperature which might be related to the deterioration of eggshell quality characteristics under heat stress. PMID:22912464
detailed characterization of the Ca2+-binding and oligomerization properties of each individual EF-hand peptide using CD spectroscopy and analytical ultracentrifugation PMID:16216075
expression of Ca-D28K in 25 sporadic cases of chicken nephroblastomas PMID:16617996
Calbindin showed a specific spatiotemporal expression pattern and was expressed in a region (area)-specific but dynamic manner during development of the hippocampus and hyperpallium. PMID:16786551
There may be a close correlation between the alpha2 subunit and calbindin in chicken nociceptive spinal neurons. PMID:17822792
Auditory-stimulated chick embryos showed a significant increase in the proportion of immunopositive neurons and the levels of expression of calbindin D-28K compared to the control at all developmental stages studied. PMID:18096144