Recombinant Chicken Cadherin-6 (CDH6), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Target Background

Product Details

Abbreviation

CDH6

Purity

>85% (SDS-PAGE)

Target Names

CDH6

Uniprot NO.

Q90762

Alternative Names

CDH6; Cadherin-6; Cadherin-6B; c-cad6B

Species

Gallus gallus (Chicken)

Source

Yeast

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.

Gene References into Functions

Cad6B C-terminal fragments possesses a novel pro-epithelial-to-mesenchymal transition (EMT) role by up-regulating EMT effector genes in vivo. PMID:27856599
Cad6B is removed from premigratory neural crest cells through cell surface internalization events that include clathrin-mediated endocytosis and macropinocytosis. PMID:25795298
A dual mechanism for Cad6B proteolysis involving two ADAMs, along with gamma-secretase, during cranial neural crest cell epithelial-to-mesenchymal transitions. PMID:24196837
the de-epithelialization step of the neural crest epithelial mesenchymal transition by cadherin-6B involves regulation of actin dynamics via LIMK/cofilin PMID:22537493
find that cadherin 6B persists in early migrating neural crest cells and is required for their emigration from the neural tube. PMID:20610481
Expression of cadherin 6B at the synaptic level on the somata and the proximal neurites of identified neuron populations has been traced selectively in the developing chicken visual system. PMID:15312902
Cadherin6B is a direct target of Snail2 repression in vivo and in the context of the EMT that characterizes neural crest development. PMID:17344227
cadherin-6B was expressed in many song nuclei of the juvenile and adult brain. PMID:18322922