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Recombinant Chicken Activin receptor type-2B (ACVR2B), partial

Recombinant Chicken Activin receptor type-2B (ACVR2B), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Target Background

Product Details

Abbreviation

ACVR2B

Purity

>85% (SDS-PAGE)

Target Names

ACVR2B

Uniprot NO.

Q90670

Alternative Names

ACVR2BActivin receptor type-2B; EC 2.7.11.30; Activin receptor type IIB; ACTR-IIB

Species

Gallus gallus (Chicken)

Source

Yeast

Expression Region

25-137

Target Protein Sequence

ETRECI YYNANWELEK TNQSGVERCE GEKDKRLHCY ASWRNNSGSI ELVKKGCWLD DFNCYDRQEC VATEENPQVF FCCCEGNYCN EKFTHLPEVT GPEVIYEPPP PTPSLLN
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A. May modulate neuropeptide expression in dorsal root ganglia (DRG) neurons and ovarian follicle development.

Gene References into Functions

This study demonstrated that the role of ACVR2B expression in ciliary ganglion neuronal development, investigating its function in neuronal differentiation and ontogenetic cell death. PMID:25660516

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Subcellular Location

Membrane; Single-pass type I membrane protein.

Protein Families

Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily

Tissue Specificity

Not expressed in hen anterior pituitary during the ovulatory cycle but expressed in the ovarian follicle.

Database Links

UNIGENE: Gga.764

KEGG: gga:374213

STRING: 9031.ENSGALP00000030643

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