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Recombinant Chicken 72 kDa type IV collagenase (MMP2), partial

Recombinant Chicken 72 kDa type IV collagenase (MMP2), partial

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MSDS	MSDS Datasheet
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Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

MMP2

Purity

>85% (SDS-PAGE)

Target Names

MMP2

Uniprot NO.

Q90611

Alternative Names

MMP2; 72 kDa type IV collagenase; EC 3.4.24.24; 72 kDa gelatinase; Gelatinase A; Matrix metalloproteinase-2; MMP-2

Species

Gallus gallus (Chicken)

Source

Yeast

Expression Region

107-663

Target Protein Sequence

YNFF PRKPKWEKNH ITYRIIGYTP DLDPETVDDA FARAFKVWSD VTPLRFNRIN DGEADIMINF GRWEHGDGYP FDGKDGLLAH AFAPGPGIGG DSHFDDDELW TLGEGQVVRV KYGNADGEYC KFPFWFNGKE YNSCTDAGRN DGFLWCSTTK DFDADGKYGF CPHESLFTMG GNGDGQPCKF PFKFQGQSYD QCTTEGRTDG YRWCGTTEDY DRDKKYGFCP ETAMSTVGGN SEGAPCVFPF IFLGNKYDSC TSAGRNDGKL WCASTSSYDD DRKWGFCPDQ GYSLFLVAAH EFGHAMGLEH SEDPGALMAP IYTYTKNFRL SQDDIKGIQE LYEVSPDVEP GPGPGPGPGP RPTLGPVTPE LCKHDIVFDG VAQIRGEIFF FKDRFMWRTV NPRGKPTGPL LVATFWPDLP EKIDAVYESP QDEKAVFFAG NEYWVYTASN LDRGYPKKLT SLGLPPDVQR IDAAFNWGRN KKTYIFSGDR YWKYNEEKKK MELATPKFIA DSWNGVPDNL DAVLGLTDSG YTYFFKDQYY LQMEDKSLKI VKIGKISSDW LGC
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

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Target Background

Gene References into Functions

Enhanced MMP-2, MMP-9 and TNF-alpha production in progressive phase correlated with sciatic nerve pathology in C. jejuni-induced Guillain-Barre syndrome in chicken model. PMID:28916318
Type I collagen promotes the expression and activation of MMPs in a lens epithelial cell-specific manner. PMID:24400880
Matrix metalloproteinase 2 (MMP2) was identified in chicken bile. Chickens fed gelatin supplements showed higher levels of bile MMP expression. Bile MMP may be associated with digestion of collagens and other extracellular matrix proteins in avian diets. PMID:24879699
The results obtained using the shell gland explants model indicate that dioxins and PCBs have a direct effect on the chicken oviduct, especially the shell gland, by affecting the expression of genes involved in the function of this oviductal segment. PMID:24279180
The results obtained indicate that in the chicken ovary MMP-2 may take part in the extracellular matrix remodelling required for follicle growth, development and regression. PMID:23342920
Endothelin-1-induced proliferation of chicken pulmonary artery smooth muscle cells (PA-SMCs) was concomitant with increased pro- and active matrix metalloproteinase (MMP)-2 production. However, PA-SMC proliferation was inhibited by two MMP inhibitors. PMID:22377328
From buds to follicles: matrix metalloproteinases in developmental tissue remodeling during feather morphogenesis PMID:21497985
At the seven-somite stage, MMP-2/Ilomastat inhibition caused a shift in normal left-right patterning of cell proliferation PMID:15844197
It is suggested that MMP-2 and MMP-9 enzymes might play a role in the permeability increase of vessel walls by the destruction of the basement membranes in the salt-induced experimental ascites syndrome in broiler chickens PMID:16537168
functional role of MMP-2 in chondrogenesis of leg bud mesenchymal cells PMID:17604018
MMP-2 is related to chondrocyte differentiation and may be involved in cartilage remodeling in the avian growth plate PMID:18344292
MMP-2/MT3-MMP are involved in the initiation and progression of fibril growth, matrix assembly, and tendon development. PMID:19221802