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Recombinant Chaetomium globosum Ubiquitin-like protein ATG12 (ATG12)

Recombinant Chaetomium globosum Ubiquitin-like protein ATG12 (ATG12)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

ATG12

Purity

>85% (SDS-PAGE)

Target Names

ATG12

Uniprot NO.

Q2GSG9

Species

Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970) (Soil fungus)

Source

Yeast

Expression Region

1-150

Target Protein Sequence

MGGAAQNNNL SNNNNDSPPA SPVLEGRDSP DLPLTMAAST ILTALPRDAT AALAAAGGFP QEKVVVRFRP VGSAPAIRRD LVKVISTHKF DSVVAYLRKM LKVPETDGVF LYINNTFAPA LDEVVGNLWR CFKDSSDHLI VSYSMSPAFG
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function(From Uniprot)

Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate functions as an E3-like enzyme which is required for lipidation of ATG8 and ATG8 association to the vesicle membranes.

Subcellular Location

Preautophagosomal structure membrane; Peripheral membrane protein.

Protein Families

ATG12 family

Database Links

STRING: 306901.XP_001227012.1

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