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Recombinant Cervus elaphus Interleukin-12 subunit beta (IL12B)

Recombinant Cervus elaphus Interleukin-12 subunit beta (IL12B)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

IL12B

Purity

>85% (SDS-PAGE)

Target Names

IL12B

Uniprot NO.

Q28234

Species

Cervus elaphus (Red deer)

Source

Yeast

Expression Region

23-327

Target Protein Sequence

IWELEKNV YVVELDWYPD APGETVVLRC DTPEEDGITW TSDQSSEVLG SGKTLTVQVK EFGDAGQYTC HKGGEVLSRS LLLLHKKEDG IWSTDILKDQ KEPKAKSFLK CEAKDYSGHF TCWWLTAIST DLKFSVKSSR GSSDPRGVTC GAASLSTEKV IVDHREYKKY TVECQEGSAC PAAEESLPIE VVVEAVHKLK YENYTSSFFI RDIIKPDPPK NLQLRPLKNS RQVEVSWEYP DTWSTPHSYF SLTFCVQVQG KNKREKKLFM DQTSAKVTCH KDASIRVQAR DRYYNSFWSE WASVSCS
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function(From Uniprot)

Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC.; Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.

Subcellular Location

Secreted.

Protein Families

Type I cytokine receptor family, Type 3 subfamily

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