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Recombinant Cat Beta-2 adrenergic receptor (ADRB2), partial

Recombinant Cat Beta-2 adrenergic receptor (ADRB2), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Target Background

Product Details

Abbreviation

ADRB2

Purity

>85% (SDS-PAGE)

Target Names

ADRB2

Uniprot NO.

Q9TST5

Species

Felis catus (Cat) (Felis silvestris catus)

Source

Yeast

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.

Gene References into Functions

In atrial myocytes, beta-AR stimulation protects against pacing-induced alternans by acting through parallel and complementary signaling pathways. PMID:22904161
Atrial cell attachment to laminin enhances zint-beta(2)-AR stimulation of I(Ca,L) via G(i)/ERK1/2/cPLA(2)/AA signalling which is activated by concomitant inhibition of cAMP/PKA signalling and dependent on the actin cytoskeleton. PMID:19703961

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Subcellular Location

Cell membrane; Multi-pass membrane protein. Early endosome. Golgi apparatus.

Protein Families

G-protein coupled receptor 1 family, Adrenergic receptor subfamily, ADRB2 sub-subfamily

Database Links

KEGG: fca:493767

STRING: 9685.ENSFCAP00000007370

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