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Recombinant Cat Beta-1 adrenergic receptor (ADRB1), partial

Recombinant Cat Beta-1 adrenergic receptor (ADRB1), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Target Background

Product Details

Abbreviation

ADRB1

Purity

>85% (SDS-PAGE)

Target Names

ADRB1

Uniprot NO.

Q9TST6

Alternative Names

ADRB1; Beta-1 adrenergic receptor; Beta-1 adrenoreceptor; Beta-1 adrenoceptor

Species

Felis catus (Cat) (Felis silvestris catus)

Source

Yeast

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling. Involved in the regulation of sleep/wake behaviors.

Gene References into Functions

In atrial myocytes, beta-AR stimulation protects against pacing-induced alternans by acting through parallel and complementary signaling pathways. PMID:22904161
3 polymorphisms identified, including one amino acid substitution PMID:21669447

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Subcellular Location

Cell membrane; Multi-pass membrane protein. Early endosome.

Protein Families

G-protein coupled receptor 1 family, Adrenergic receptor subfamily, ADRB1 sub-subfamily

Database Links

KEGG: fca:493971

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