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Recombinant Bovine Tumor necrosis factor receptor superfamily member 11B (TNFRSF11B)

Recombinant Bovine Tumor necrosis factor receptor superfamily member 11B (TNFRSF11B)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

TNFRSF11B

Uniprot NO.

A5D7R1

Alternative Names

TNFRSF11B; Tumor necrosis factor receptor superfamily member 11B; Osteoprotegerin

Species

Bos taurus (Bovine)

Source

Yeast

Expression Region

22-402

Target Protein Sequence

ETFPPKYLH YDPESSRQLM CDKCPPGTFL KQPCTARRKT VCAPCPDHYY TDTWHTSDEC LYCSPVCKEL QYVKQECSRT HNRVCECEEG RYLELEFCLK HRSCPPGFGV LHPGTPERNT VCKRCPDGFF SNETSSKAPC RKHTNCSAFG LLLTQKGNAT HDNICSGSSE SSTHKCGIDM TLCEEAFFRF AVPTKLTPNW LSVLVDNLPG TKVNAESIER IKQRHNSREQ TFQLLKLWKH QNKDQDMVKK IIQDIDLCEN SVRRHIGHLN LTFEQLLKLM ESLPGKKVTT EDVEKTVKTC KSSEQLLKLL SLWRIKNGDQ DTRKGLLHAL KHLKTYHFPK TVIQSLKKTI RFLHSFTMYR LYRKLFLEMI GNQVQSLKIS CL
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function(From Uniprot)

Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. May also play a role in preventing arterial calcification. May act as decoy receptor for TNFSF10/TRAIL and protect against apoptosis. TNFSF10/TRAIL binding blocks the inhibition of osteoclastogenesis.

Subcellular Location

Secreted.

Database Links

UNIGENE: Bt.40061

KEGG: bta:523822

STRING: 9913.ENSBTAP00000009759

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