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Recombinant Bovine Thyrotropin subunit beta (TSHB)

Recombinant Bovine Thyrotropin subunit beta (TSHB)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

TSHB

Uniprot NO.

P01223

Alternative Names

TSHB; Thyrotropin subunit beta; Thyroid-stimulating hormone subunit beta; TSH-B; TSH-beta; Thyrotropin beta chain

Species

Bos taurus (Bovine)

Source

Yeast

Expression Region

21-132

Target Protein Sequence

FCIPTEYMMH VERKECAYCL TINTTVCAGY CMTRDVNGKL FLPKYALSQD VCTYRDFMYK TAEIPGCPRH VTPYFSYPVA ISCKCGKCNT DYSDCIHEAI KTNYCTKPQK SY
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Indispensable for the control of thyroid structure and metabolism.

Gene References into Functions

Nitric oxide decreases TSH-induced FoxE1 expression, thus repressing the transcripcional activation of TPO gene. PMID:26610751
identification for the first time that ADAM10 is a TSHR cleavage enzyme and demonstration that TSH regulates its activation PMID:18074395

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Subcellular Location

Secreted.

Protein Families

Glycoprotein hormones subunit beta family

Database Links

UNIGENE: Bt.475

KEGG: bta:281552

STRING: 9913.ENSBTAP00000008264

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