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Recombinant Bovine Thrombospondin-2 (THBS2), partial

Recombinant Bovine Thrombospondin-2 (THBS2), partial

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

THBS2

Purity

>85% (SDS-PAGE)

Target Names

THBS2

Uniprot NO.

Q95116

Species

Bos taurus (Bovine)

Source

Yeast

Expression Region

19-1170

Target Protein Sequence

GD QDEDTAFDLF SISNINRKTI GAKQFRGPDP SVPAYRFVRF DYIPPVSAEH LGRITEAMRR KEGFFLTASM KQDRRSRGTL LALEGPGATH RQFEIVSNGP ADTLDLTYWV DGTQHVISLE DVGLADSQWK NVTVQVTGET YSLYVGCDLM DSFALDEPFY EHLQTERSRM YVTKGAARES HFRGLLQNVY LVFENSVEDL LSKKGCQQSQ GAETNAISEN TETLHLSPMV TMEHVGPSAE KSPEVCEHSC EELGSMIREL SGLHVIVNQL HENLRKVSND NQFLWELIGG PPKTRNVSAC WQDGRFFAEN ETWVVDSCTK CTCKKFKTVC HQISCPPATC ADPWFVEGEC CPSCVHDGEE GWSPWAEWTE CSATCGSGTQ QRGRSCDVTS NTCLGPSIQT RACSLGRCDH RIRQDGGWSH WSPWSSCSVT CGVGNVTRIR LCNSPVPQMG GRSCKGSGRE TKACQGPPCP VDGRWSPWSP WSACTVTCAG GIRERTRVCN SPEPQHGGKD CVGGAKEQQM CNRKSCPIDG CLSNPCFPGA ECSSFPDGSW SCGSCPGGFL GNGTHCEDLD ECAVVTDVCF ATSKAHRCVN TNPGYHCLPC PPRYKGNQPF GVGLEAARTE KQVCEPENPC KDKTHSCHRH AECIYLGHFS DPMYKCECQT GYAGDGLICG EDSDLDGWPN KNLVCATNAT YHCVKDNCPL LPNSGQEDFD KDGIGDACDD DDDNDGVSDE KDNCQLLFNP RQFDYDKDEV GDRCDNCPYV HNPAQIDTDN NGEGDACSVD IDGDDVFNER DNCPYVYNTD QRDTDGDGVG DHCDNCPLVH NPDQTDVDND LVGDQCDNNE DIDEDGHQNN QDNCPHIPNA NQADHDRDGQ GDACDSDDDN DGIPDDRDNC RLVANPDQED SDGDRRGDAC KDDFDNDSIP DIDDVCPENN AISETDFRNF QMVHLDPKGT TQIDPNWVIR HQGKELVQTA NSDPGIAVGF DEFGSVDFSG TFYVNTDRDD DYAGFVFGYQ SSSRFYVVMW KQVTQTYWED QPTRAYGYSG VSLKVVNSTT GTGEHLRNAL WHTGNTEGQV RTLWHDPKNI GWKDYTAYRW HLTHRPKTGY IRVLVHEGKQ VMADSGPIYD QTYAGGRLGL FVFSQEMVYF SDLKYECRDV
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

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Target Background

Function(From Uniprot)

Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Ligand for CD36 mediating antiangiogenic properties.

Gene References into Functions

temporal expression and localization pattern of the thrombospondins and their specific receptors in the antral follicles and corpora lutea during the different physiological phases of the estrous cycle and induced luteolysis appear to be compatible with their inhibitory role in the control of ovarian angiogenesis PMID:27396384
Data suggest THBS1 expression predominates in luteal endothelial cells; THBS2 expression predominates in luteinized granulosa cells. Luteinization down-regulates expression of THBS1/THBS2, up-regulates expression of FGF2 (fibroblast growth factor 2). PMID:25061096
TSP-1 and -2 were coordinately expressed in the extravascular compartment of the ovary during early follicle development. VEGF was inversely expressed, with expression increasing as follicles developed. PMID:15616224

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Protein Families

Thrombospondin family

Database Links

UNIGENE: Bt.5522

KEGG: bta:338092

STRING: 9913.ENSBTAP00000042078

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