Recombinant Bovine Synapsin-1 (SYN1), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

SYN1

Uniprot NO.

P17599

Alternative Names

SYN1; Synapsin-1; Synapsin I

Species

Bos taurus (Bovine)

Source

Yeast

Expression Region

1-706

Target Protein Sequence

MNYLRRRLSD SNFMANLPNG YMTDLQRPQP PPPPPAAPSP GATTGPATAT AERASSAAPV ASPAAPSPGS SGGGGFFSSL SNAVKQTTAA AAATFSEQVG GGSGGAGRGG AAARVLLVID EPHTDWAKYF KGKKIHGEID IKVEQAEFSD LNLVAHANGG FSVDMEVLRN GVKVVRSLKP DFVLIRQHAF SMARNGDYRS LVIGLQYAGI PSINSLHSVY NFCDKPWVFA QMVRLHKKLG TEEFPLINQT FYPNHKEMLS STTYPVVVKM GHAHSGMGKV KVDNQHDFQD IASVVALTKT YATTEPFIDA KYDVRIQKIG QNYKAYMRTS VSGNWKTNTG SAMLEQIAMS DRYKLWVDTC SEIFGGLDIC AVEALHGKDG RDHIIQVVGS SMPLIGDHQD EDKQLIVELV VNKMAQALPR QRQRDASPGR GSHSQTPSPG ALPLGRQISQ QPAGPPAQQR PPPQGGPPQP GPGPQRQGPP LQQRPTPQGQ QHLSGLGPPA GSPLPQRLPS PTSVPQQPAS QATPMTQGQG RQSRPVAGGP GAPPATRPPA SPSPQRQAGP PQATRQTSVS GQAPPKASGV PPGGQQRQGP PQKPPGPAGP TRQASQAGPM PRTGPPTTQQ PRPSGPGPAG RPTKPQLAQK PSQDVPPPAT AAAGGPPHPQ LNKSQSLTNA FNLPEPAPPR PSLSQDEVKA ETIRSLRKSF ASLFSD
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level.

Gene References into Functions

These results raise the possibility that Ser(603) on synapsin I is alternatively phosphorylated by p21-activated kinases, not only by CaMKII, in neuronal cells in response to some stimulants. PMID:12237306
Synapsin acts as a phosphorylation-modulated mediator of feedback regulation of Gz signaling by the synaptic machinery PMID:14557263
Synapsin-Rab3 interaction may participate in the regulation of synaptic vesicle trafficking within the nerve terminals. PMID:15265865
Interacts with rab3 protein; this interaction is likely to play a major role in the modulation of neurotransmitter release. PMID:15265868