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Recombinant Bovine Sodium/hydrogen exchanger 1 (SLC9A1), partial

Recombinant Bovine Sodium/hydrogen exchanger 1 (SLC9A1), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Target Background

Product Details

Abbreviation

SLC9A1

Purity

>85% (SDS-PAGE)

Target Names

SLC9A1

Uniprot NO.

Q28036

Alternative Names

SLC9A1; NHE1; Sodium/hydrogen exchanger 1; Na(+)/H(+) exchanger 1; NHE-1; Solute carrier family 9 member 1

Species

Bos taurus (Bovine)

Source

Yeast

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.

Gene References into Functions

This study evaluated the role for NHE-1 in diabetic cataract formation and retinal oxidative stress and apoptosis. PMID:22407349
Results support the hypothesis that a blood-brain barrier Na/H exchanger, possibly NHE1 and/or NHE2, is stimulated during ischemia to participate in cerebral edema formation. PMID:19458287

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Subcellular Location

Membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.

Protein Families

Monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family

Database Links

UNIGENE: Bt.528

KEGG: bta:317654

STRING: 9913.ENSBTAP00000048292

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