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Recombinant Bovine Signal transducer and activator of transcription 5B (STAT5B), partial

Recombinant Bovine Signal transducer and activator of transcription 5B (STAT5B), partial

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

STAT5B

Purity

>85% (SDS-PAGE)

Target Names

STAT5B

Uniprot NO.

Q9TUM3

Alternative Names

STAT5B; Signal transducer and activator of transcription 5B

Species

Bos taurus (Bovine)

Source

Yeast

Expression Region

1-787

Target Protein Sequence

MAVWIQAQQL QGDALHQMQA LYGQHFPIEV RHYLSQWIEG QAWDSIDLDN PQENIKATQL LEGLVQELQK KAEHQVGEDG FLLKIKLGHY ATQLQNTYDR CPMELVRCIR HILYNEQRLV REANNGTSPA GSLADAMSQK HLQINQTFEE LRLVTQDTEN ELKKLQQTQE YFIIQYQESL RIQAQFAQLA QLNPQERLSR ETALQQKQLS LEAWLQREAQ TLQQYRVELA EKHQKTLQLL RKQQTIILDD ELIQWKRRQQ LAGNGGPPEG SLDVLQSWCE KLAEIIWQNR QQIRRAEHFC QQLPIPGPVE EMLAEVNATI TDIISALVTS TFIIEKQPPQ VLKTQTKFAA TVRLLVGGKL NVHMNPPQVK ATIISEQQAK SLLKNENTRN DYSGEILNNC CVMEYHQATG TLSAHFRNMS LKRIKRSDRR GAESVTEEKF TILFESQFSV GGNELVFQVK TLSLPVVVIV HGSQDNNATA TVLWDNAFAE PGRVPFAVPD KVLWPQLCEA LNMKFKAEVQ SNRGLTKENL VFLAQKLFNS SSSHLEDYNG MSVSWSQFNR ENLPGRNYTF WQWFDGVMEV LKKHLKPHWN DGAILGFVNK QQAHDLLINK PDGTFLLRFS DSEIGGITIA WKFDSQERMF WNLMPFTTRD FSIRSLADRL GDLSYLIYVF PDRPKDEVYS KYYTPVPCEP ATAKAVDGYV KPQIKQVVPE FVSASADSAG GSATYMDQAP SPAVCPQPHY NMYPQNPDPV LDNDGDFDLD DTIDVARRVE ELLGRPMDSQ WIPHAQS
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function(From Uniprot)

Carries out a dual signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Binds to the GAS element and activates PRL-induced transcription. Positively regulates hematopoietic/erythroid differentiation.

Gene References into Functions

SNPs in JAK2 and STAT5B are associated with mastitis susceptibility in Chinese Holstein cattle PMID:26154111
This study suggests that growth hormone inhibits the differentiation of bovine preadipocytes to adipocytes through STAT5b-dependent inhibition of C/EBPalpha and PPARgamma expression. PMID:24668956
These results suggested that the SNPs in CD4 and STAT5b may be potential genetic markers for SCS and milk/protein yields selecting and warrant further functional research. PMID:21435309

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Subcellular Location

Cytoplasm. Nucleus.

Protein Families

Transcription factor STAT family

Database Links

UNIGENE: Bt.20143

KEGG: bta:282376

STRING: 9913.ENSBTAP00000012497

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