Recombinant Bovine Ras GTPase-activating protein 1 (RASA1), partial

Product Details

Purity
>85% (SDS-PAGE)
Target Names
RASA1
Uniprot NO.
Alternative Names
RASA1; RASA; Ras GTPase-activating protein 1; GAP; GTPase-activating protein; RasGAP; Ras p21 protein activator; p120GAP
Species
Bos taurus (Bovine)
Source
Yeast
Expression Region
1-1044
Target Protein Sequence
MMAAEAGGEE GGPVTAGAAG GGAAAASGAY PAVCRVKIPA ALPVAAAAPF PGLAEAGVAA TLGGGAALGS GFLGAGSVAG TPGGVGLSAG GAAAGVAGVA AAAAGAGGEM AFAKGTTSLP TETFGAGGGF PPLPPPPPQL PTLGAGLGTV DEGDSLDGPE YEEEEVAIPL TAPPTNQWYH GKLDRTIAEE RLRQAGKSGS YLIRESDRRP GSFVLSFLSQ TNVVNHFRII AMCGDYYIGG RRFSSLSDLI GYYSHVSCLL KGEKLLYPVA PPEPVEDRRR VRAILPYTKV PDTDEISFLK GDMFIVHNEL EDGWMWVTNL RTDEQGLIVE DLVEEVGREE DPHEGKIWFH GKISKQEAYN LLMTVGQACS FLVRPSDNTP GDYSLYFRTS ENIQRFKICP TPNNQFMMGG RYYNSIGDII DHYRKEQIVE GYYLKEPVPM QDQEQVLNDA VDGKEIYNTI RRKTKDAFYK NIVKKGYLLK KGKGKRWKNL YFILEGSDAQ LIYFESEKRA TKPKGLIDLS VCSVYVVHDS LFGRPNCFQI VVQHFSEEHY IFYFAGETPE QAEDWMKGLQ AFCNLRKSSP GTSNKRLRQV SSLILHIEEA HKLPVKHFTN PYCNIYLNSV QVAKTHAREG QNPVWSEEFV FDDLPPDINR FEITLSNKTK KSKDPDILFM RCQLSRLQKG HATDEWFLLS SHIPLKGIEP GSLRVRARYS MEKIMPEEEY SEFKELILQK ELHVVYALSH VCGQDRTLLA SILLKIFLHE KLESLLLCTL NDREISMEDE ATTLFRATTL ASTLMEQSMK ATATQFVHHA LKDSILRIME SKQSCELSPS KLEKNEDVNT NLAHLLNILS ELVEKIFMAS EILPPTLRYI YGCLQKSVQH KWPTNTTMRT RVVSGFVFLR LICPAILNPR MFNIISDSPS PIAARTLTLV AKSVQNLANL VEFGAKEPYM EGVNPFIKSN KHRMIMFLDE LGNVPELPDT TEHSRTDLCR DLAALHEICV AHSDELRTLS NERGAQQHVL KKLLAITELL QQKQNQYTKT NDVR
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
Protein Length
Partial
Tag Info
N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage Condition
Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)
Inhibitory regulator of the Ras-cyclic AMP pathway. Stimulates the GTPase of normal but not oncogenic Ras p21.
Gene References into Functions
  1. The data suggest that nitrosylation of H-Ras rearranges the adsorptive potential and intrinsic GTPase activity of H-Ras through modification of C-terminal cysteines of molecule. PMID:21103953

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Subcellular Location
Cytoplasm.
Database Links
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