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Recombinant Bovine Prostaglandin E synthase 2 (PTGES2)

Recombinant Bovine Prostaglandin E synthase 2 (PTGES2)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

PTGES2

Purity

>85% (SDS-PAGE)

Target Names

PTGES2

Uniprot NO.

Q66LN0

Alternative Names

PTGES2; PGES2Prostaglandin E synthase 2; EC 5.3.99.3; Membrane-associated prostaglandin E synthase-2; mPGE synthase-2; Microsomal prostaglandin E synthase 2; mPGES-2) [Cleaved into: Prostaglandin E synthase 2 truncated form]

Species

Bos taurus (Bovine)

Source

Yeast

Expression Region

1-79

Target Protein Sequence

ERSATQLSLS SRLQLTLYQY KTAEIKFSSY RKVPILVAQE GESLQQLNDS SVIISALKTY LVSGQPLADI ITYYPAMKA
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Isomerase that catalyzes the conversion of PGH2 into the more stable prostaglandin E2 (PGE2) (in vitro). The biological function and the GSH-dependent property of PTGES2 is still under debate. In vivo, PTGES2 could form a complex with GSH and heme and would not participate in PGE2 synthesis but would catalyze the degradation of prostaglandin E2 H2 (PGH2) to 12(S)-hydroxy-5(Z),8(E),10(E)-heptadecatrienoic acid (HHT) and malondialdehyde (MDA).

Subcellular Location

Microsome membrane; Single-pass membrane protein.; [Prostaglandin E synthase 2 truncated form]: Cytoplasm.

Protein Families

GST superfamily

Tissue Specificity

Detected in heart (at protein level). Widely expressed. Expressed in heart > kidney > muscle > testis > endometrium = ovary > myometrium = spleen = lung. In endometrium, it is mainly expressed in luminal epithelial cells followed by glandular epithelial c

Database Links

UNIGENE: Bt.34207

KEGG: bta:493639

STRING: 9913.ENSBTAP00000021584

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