Recombinant Bovine Pro-opiomelanocortin (POMC)

Product Details

Purity
>85% (SDS-PAGE)
Target Names
POMC
Uniprot NO.
Alternative Names
POMCPro-opiomelanocortin; POMC; Corticotropin-lipotropin) [Cleaved into: NPP; Melanotropin gamma; Gamma-MSH); Corticotropin; Adrenocorticotropic hormone; ACTH); Melanocyte-stimulating hormone alpha; Alpha-MSH; Melanotropin alpha); Corticotropin-like intermediary peptide; CLIP); Lipotropin beta; Beta-LPH); Lipotropin gamma; Gamma-LPH); Melanocyte-stimulating hormone beta; Beta-MSH; Melanotropin beta); Beta-endorphin; Met-enkephalin]
Species
Bos taurus (Bovine)
Source
Yeast
Expression Region
27-103
Target Protein Sequence
WCLE SSQCQDLTTE SNLLACIRAC KPDLSAETPV FPGNGDEQPL TENPRKYVMG HFRWDRFGRR NGSSSSGVGG AAQ
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
Protein Length
Cytoplasmic domain
Tag Info
N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage Condition
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
Stimulates the adrenal glands to release cortisol.; Anorexigenic peptide. Increases the pigmentation of skin by increasing melanin production in melanocytes.; Endogenous orexigenic opiate.; Endogenous opiate.
Gene References into Functions
  1. The association has been reported between polymorphisms of the CRH and POMC genes with economic traits in Korean cattle. PMID:26400272
  2. Expression of the hepatic endocannabinoid system and proopiomelanocortin was altered by plane of dietary energy prepartum particularly during the first 2-week postpartum. PMID:21812840
  3. Significant associations were observed between POMC c.288C>T with start-of-finishing weight (SOF WT; P = 0.04), hot carcass weight (HCW; P = 0.02), average fat and grade fat (both P = 0.05), carcass rib-eye area (REA; P = 0.03) and marbling PMID:21205304
  4. The polymorphism of POMC gene is associated with the growth traits of Nanyang cattle. PMID:20042389

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Subcellular Location
Secreted.
Protein Families
POMC family
Tissue Specificity
ACTH and MSH are produced by the pituitary gland.
Database Links

UNIGENE: Bt.8797

KEGG: bta:281416

STRING: 9913.ENSBTAP00000010386

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