Recombinant Bovine Oncostatin-M (OSM)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

OSM

Uniprot NO.

P53346

Species

Bos taurus (Bovine)

Source

Yeast

Expression Region

27-205

Target Protein Sequence

KCSG KYHELLLQLQ RQADLMQDPS TLLDPYIHLQ GLHSPVLQEH CRERPGDFPS EDALWRLSRQ DFLQTLNTTL GLILRMLSAL QQDLPEAAHQ QAEMNVRGFG NNIHCMAQLL RGSSDPKAAE PTQPGPGPTP LPPTPPSSTF QRKLRNCGFL RGYHRFMRTA GQVLRGWGER QGRSR
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Growth regulator. Inhibits the proliferation of a number of tumor cell lines. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIFR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration.

Subcellular Location

Secreted.

Protein Families

LIF/OSM family

Database Links

STRING: 9913.ENSBTAP00000021515

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