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Recombinant Bovine Nuclear receptor subfamily 4 group A member 1 (NR4A1), partial

Recombinant Bovine Nuclear receptor subfamily 4 group A member 1 (NR4A1), partial

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Target Background

Product Details

Abbreviation

NR4A1

Purity

>85% (SDS-PAGE)

Target Names

NR4A1

Uniprot NO.

Q0V8F0

Alternative Names

NR4A1; Nuclear receptor subfamily 4 group A member 1

Species

Bos taurus (Bovine)

Source

Yeast

Expression Region

1-598

Target Protein Sequence

MPCIQAQYGT PAPSPGPRDH LAGDLLTPEL SKPTMDLASP EAAPAVPTAL PSFSTFMDGY TGEFDTFLYQ LSGTAQPCSS ASSSASSTSS SSATSPASAS FKFEDFQVYG CYPGTLSGPL DETLSSSGSD YYGSPCSAPS PSTPSFQPPQ LSPWDGSFGP FSPSQTYEGL RAWTEQLPKA SGPPQPPAFF SFSPPPGPSP SLAPSPLKLF PSQAAHQLGE GESYSMQTAF PGLVPTSPHL DGSGRLDAPV TSAKARSGAP GGSEGRCAVC GDNASCQHYG VRTCEGCKGF FKRTVQKNAK YICLANKDCP VDKRRRNRCQ FCRFQKCLAV GMVKEVVRTD SLKGRRGRLP SKPKQPPETS PAHLLTSLVR AHLDSGPSTS KLDYSKFQEL ALPHFGKEDA GDVQQFYDLL SGSLEVIRKW AEKIPGFAEL SPGDQDLLLE SAFLELFILR LAYRSKPAEG KLIFCSGLVL HRLQCARGFG DWIDSILAFS RSLHSLVVDI PAFACLSALV LITDRHGLQE PRRVEELQNR IASCLKEHVS AEAGEPQPAS CLSRLLGKLP ELRTLCTQGL QRIFYLKLED LVPPPPIVDK IFMDTLPF
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

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Target Background

Function(From Uniprot)

Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3'. May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation. Plays a role in the vascular response to injury.

Gene References into Functions

Identify the orphan nuclear receptor NR4A1 as a potential early response gene in FGF2 signaling and regulation of sprouty in bovine ovarian granulosa cells. PMID:21506113

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Subcellular Location

Nucleus. Cytoplasm. Mitochondrion.

Protein Families

Nuclear hormone receptor family, NR4 subfamily

Database Links

UNIGENE: Bt.23373

KEGG: bta:528390

STRING: 9913.ENSBTAP00000000648

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