Recombinant Bovine Natriuretic peptides B (NPPB)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

NPPB

Uniprot NO.

P13204

Alternative Names

NPPBNatriuretic peptides B; Gamma-brain natriuretic peptide) [Cleaved into: Aldosterone secretion inhibitory factor; ASIF); Brain natriuretic peptide 26; BNP-26)]

Species

Bos taurus (Bovine)

Source

Yeast

Expression Region

27-129

Target Protein Sequence

HPVG GPGPVSELPG LQELLDRLRD RVSELQAEQL RVEPLQQGQG LEETWDSPAA APAGFLGPHH SILRALRGPK MMRDSGCFGR RLDRIGSLSG LGCNVLRRY
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Cardiac hormone that plays a key role in mediating cardio-renal homeostasis. May also function as a paracrine antifibrotic factor in the heart. Acts by specifically binding and stimulating NPR1 to produce cGMP, which in turn activates effector proteins that drive various biological responses. Involved in regulating the extracellular fluid volume and maintaining the fluid-electrolyte balance through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Binds the clearance receptor NPR3.

Subcellular Location

Secreted.; [Aldosterone secretion inhibitory factor]: Secreted.

Protein Families

Natriuretic peptide family

Database Links

UNIGENE: Bt.30348

KEGG: bta:508734

STRING: 9913.ENSBTAP00000028974

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