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Recombinant Bovine NF-kappa-B essential modulator (IKBKG)

Recombinant Bovine NF-kappa-B essential modulator (IKBKG)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

IKBKG

Purity

>85% (SDS-PAGE)

Target Names

IKBKG

Uniprot NO.

Q95KU9

Species

Bos taurus (Bovine)

Source

Yeast

Expression Region

1-419

Target Protein Sequence

MSRPPWKSPL CEMVQPSGSP AGDQDMLGEE SSLGKPAMLH VPSEQGTPET FQRCLEENQE LRDAIRQSNQ MLRERCEELQ HFQGNQREEK AFLMQKFQEA RDLVVRLSLE KRELRQQREQ ALKEVERLKT CQQQMAEDKA SVKAQVTSLL GELQESQSRL EAATKERQAL ESRARVASEK ARQLESEREA LEQRHSVQVD QLVLQNESME AALRMERQAA SEEKRKLAQL QVAYHQLFQE YDNHMKSSMV SSERNRGLQL EDLKQQLQQA EEALVAKQEV IDKLKEEAEQ HKIVMETVPV LKAQADIYKA DFQAERQARE KLAEKKEFLQ EQLEQLQREY SRLKTSCQES ARIEDMRKRH VEVSQPPLAP GPAHHSFHLN PSSQRRSPPD EPPKFCCPKC QYQAPDIDTL QIHVMECIE
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function(From Uniprot)

Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin plays a key role in IKK activation by multiple signaling receptor pathways. Can recognize and bind both 'Lys-63'-linked and linear polyubiquitin upon cell stimulation, with a much highr affinity for linear polyubiquitin. Could be implicated in NF-kappa-B-mediated protection from cytokine toxicity. Essential for viral activation of IRF3. Involved in TLR3- and IFIH1-mediated antiviral innate response; this function requires 'Lys-27'-linked polyubiquitination.

Subcellular Location

Cytoplasm. Nucleus.

Database Links

UNIGENE: Bt.98727

KEGG: bta:281855

STRING: 9913.ENSBTAP00000008224

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