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Recombinant Bovine Leukemia inhibitory factor (LIF)

Recombinant Bovine Leukemia inhibitory factor (LIF)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

LIF

Purity

>85% (SDS-PAGE)

Target Names

LIF

Uniprot NO.

Q27956

Species

Bos taurus (Bovine)

Source

Yeast

Expression Region

23-202

Target Protein Sequence

SPLPITPV NATCATRHPC PSNLMNQIRN QLGQLNSSAN SLFILYYTAQ GEPFPNNLDK LCSPNVTDFP PFHANGTEKA RLVELYRIIA YLGASLGNIT RDQKVLNPYA HGLHSKLSTT ADVLRGLLSN VLCRLCSKYH VSHVDVTYGP DTSGKDVFQK KKLGCQLLGK YKQVIAVLAQ AF
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes.

Gene References into Functions

Studied the effects of leukemia inhibitory factor (LIF) on bovine oocyte maturation and early embryo development in vitro. PMID:24687528
results suggest that leukemia inhibitory factor and macrophage-colony stimulating factor are produced in the endometrium and may play different roles in early and mid-pregnancy PMID:14511776

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Subcellular Location

Secreted.

Protein Families

LIF/OSM family

Database Links

UNIGENE: Bt.493

KEGG: bta:280840

STRING: 9913.ENSBTAP00000009761

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