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Recombinant Bovine Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1)

Recombinant Bovine Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1)

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Target Background

Product Details

Abbreviation

IDH1

Purity

>85% (SDS-PAGE)

Target Names

IDH1

Uniprot NO.

Q9XSG3

Alternative Names

IDH1; ICDHIsocitrate dehydrogenase [NADP] cytoplasmic; IDH; EC 1.1.1.42; Cytosolic NADP-isocitrate dehydrogenase; IDP; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase

Species

Bos taurus (Bovine)

Source

Yeast

Expression Region

2-414

Target Protein Sequence

SQKIQGGSV VEMQGDEMTR IIWELIKEKL IFPYVELDLH SYDLGIENRD ATNDQVTKDA AEAIKKYNVG VKCATITPDE KRVEEFKLKQ MWKSPNGTIR NILGGTVFRE AIICKNIPRL VSGWVKPIII GRHAYGDQYR ATDFVVPGPG KVEISYTPSD GSPKTVYLVH NFTESGGVAM GMYNQDKSIE DFAHSSFQMA LSKNWPLYLS TKNTILKKYD GRFKDIFQEI YDKQYKSEFE AQNIWYEHRL IDDMVAQAMK SEGGFIWACK NYDGDVQSDS VAQGYGSLGM MTSVLVCPDG KTVEAEAAHG TVTRHYRMYQ KGQETLTNPI ASIFAWTRGL AHRAKLDNNK ELSFFAKALE EVCIETIEAG FMTKDLAACI KGLPNVQRSD YLNTFEFMDK LGENLQLKLA QAKL
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

May act as a corneal epithelial crystallin and may be involved in maintaining corneal epithelial transparency.

Gene References into Functions

Data suggest that the expression of cytosolic NADP+-dependent isocitrate dehydrogenase in bovine mammary epithelium is modulated by regulators of differentiation including extracellular matrix and lactogenic hormones as well as metabolic effectors. PMID:16636309

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Subcellular Location

Cytoplasm, cytosol.

Protein Families

Isocitrate and isopropylmalate dehydrogenases family

Tissue Specificity

Expressed preferentially in corneal epithelium. Constitute approximately 13% of the total soluble bovine corneal epithelial proteins.

Database Links

UNIGENE: Bt.13324

KEGG: bta:281235

STRING: 9913.ENSBTAP00000027348

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