Recombinant Bovine Growth/differentiation factor 9 (GDF9)

Product Details

Abbreviation
GDF9
Purity
>85% (SDS-PAGE)
Target Names
GDF9
Uniprot NO.
Species
Bos taurus (Bovine)
Source
Yeast
Expression Region
319-453
Target Protein Sequence
DQ ESVSSELKKP LVPASFNLSE YFKQFLFPQN ECELHDFRLS FSQLKWDNWI VAPHKYNPRY CKGDCPRAVG HRYGSPVHTM VMNIIHEKLD SSVPRPSCVP AKYSPLSVLA IEPDGSIAYK EYEDMIATKC TCR
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
Protein Length
Full Length of Mature Protein
Tag Info
N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
Required for ovarian folliculogenesis.
Gene References into Functions
  1. This study concluded that the improved pregnancy rate after porcine LH-induced ovulation reported previously occurred through greater activation of intrafollicular transforming growth factor-beta1 superfamily members, as these proteins promote cumulus expansion and oocyte competence. PMID:26794084
  2. Genetic variability is an important component of the number of antral follicles in the bovine ovary. PMID:22959639
  3. Immunization against GDF9 and BMP15, alone or together, altered follicular development and ovulation rate in cattle. PMID:19439562
  4. GDF9 expression in the oocytes of calf ovaries was significantly higher than in those of the adult ovaries PMID:21401961
  5. GDF-9 mediates its effect through the pathway commonly activated by TGF beta and activin, but not that activated by many BMPs PMID:12574210
  6. Maternal GDF9 transcripts persisted during oocyte in vitro maturation and fertilization and in preimplantation embryo until the five- to eight-cell or morula stage, but transcription was not reactivated at the time of embryonic genome activation. PMID:15189828
  7. Oocyte- and granulosa cell-derived GDF9 may simultaneously promote theca cell proliferation and prevent premature differentiation of the theca interna during early follicle development. PMID:17959852

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Subcellular Location
Secreted.
Protein Families
TGF-beta family
Database Links

UNIGENE: Bt.7047

KEGG: bta:282574

STRING: 9913.ENSBTAP00000012476

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