Recombinant Bovine Fibulin-5 (FBLN5)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

FBLN5

Purity

>85% (SDS-PAGE)

Target Names

FBLN5

Uniprot NO.

Q5EA62

Species

Bos taurus (Bovine)

Source

Yeast

Expression Region

24-448

Target Protein Sequence

QQQCTNG FDLDRSSGQC LDVDECRTIP EACRGDMMCV NQNGGYLCIP RTNPVYRGPY SNPYSNPYSA SYPAAAPPLS APNYPTISRP LICRFGYQMD ESNQCVDVDE CATDSHQCNP TQICINTEGG YTCSCTDGYW LLEGQCLDID ECRYGYCQQL CANVPGSYSC TCNPGFTLNE DGRSCQDVNE CATENPCVQT CVNTYGSFIC RCDPGYELED DGVHCSDMDE CSFSEFLCQH ECVNQPGTYF CSCPAGYILL DDNRSCQDIN ECEHRNHTCI LQQTCYNLQG GFKCIDPIRC EEPYLRISDN RCMCPAENPG CRDQPFTILY RDMDVVSGRS VPADIFQMQA TTRYPGAYYI FQIKSGNDGR EFYMRQTGPI SATLVMTRPI KGPRDIQLDL EMITVNTVIN FRGSSVIRLR IYVSQYPF
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Essential for elastic fiber formation, is involved in the assembly of continuous elastin (ELN) polymer and promotes the interaction of microfibrils and ELN. Stabilizes and organizes elastic fibers in the skin, lung and vasculature. Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Vascular ligand for integrin receptors which may play a role in vascular development and remodeling. May act as an adapter that mediates the interaction between FBN1 and ELN.

Gene References into Functions

These results suggest a novel regulatory mechanism of elastic fiber assembly in which LTBP-2 regulates targeting of DANCE on suitable microfibrils to form elastic fibers. PMID:17581631

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Subcellular Location

Secreted. Secreted, extracellular space, extracellular matrix.

Protein Families

Fibulin family

Database Links

UNIGENE: Bt.44183

KEGG: bta:535185

STRING: 9913.ENSBTAP00000024122

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