Recombinant Bovine Fibronectin (FN1), partial

Baculovirus
Mammalian cell

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

FN1

Uniprot NO.

P07589

Alternative Names

FN1Fibronectin; FN) [Cleaved into: Anastellin]

Species

Bos taurus (Bovine)

Source

Yeast

Expression Region

33-2478

Target Protein Sequence

QAQQIVQP QSPLTVSQSK PGCYDNGKHY QINQQWERTY LGSALVCTCY GGSRGFNCES KPEPEETCFD KYTGNTYRVG DTYERPKDSM IWDCTCIGAG RGRISCTIAN RCHEGGQSYK IGDTWRRPHE TGGYMLECVC LGNGKGEWTC KPIAEKCFDQ AAGTSYVVGE TWEKPYQGWM MVDCTCLGEG SGRITCTSRN RCNDQDTRTS YRIGDTWSKK DNRGNLLQCI CTGNGRGEWK CERHTSLQTT SAGSGSFTDV RTAIYQPQPH PQPPPYGHCV TDSGVVYSVG MQWLKTQGNK QMLCTCLGNG VSCQETAVTQ TYGGNSNGEP CVLPFTYNGK TFYSCTTEGR QDGHLWCSTT SNYEQDQKYS FCTDHTVLVQ TRGGNSNGAL CHFPFLYNNH NYTDCTSEGR RDNMKWCGTT QNYDADQKFG FCPMAAHEEI CTTNEGVMYR IGDQWDKQHD MGHMMRCTCV GNGRGEWTCV AYSQLRDQCI VDGITYNVND TFHKRHEEGH MLNCTCFGQG RGRWKCDPVD QCQDSETRTF YQIGDSWEKY LQGVRYQCYC YGRGIGEWAC QPLQTYPDTS GPVQVIITET PSQPNSHPIQ WSAPESSHIS KYILRWKPKN SPDRWKEATI PGHLNSYTIK GLRPGVVYEG QLISVQHYGQ REVTRFDFTT TSTSPAVTSN TVTGETTPLS PVVATSESVT EITASSFVVS WVSASDTVSG FRVEYELSEE GDEPQYLDLP STATSVNIPD LLPGRKYTVN VYEISEEGEQ NLILSTSQTT APDAPPDPTV DQVDDTSIVV RWSRPRAPIT GYRIVYSPSV EGSSTELNLP ETANSVTLSD LQPGVQYNIT IYAVEENQES TPVFIQQETT GVPRSDKVPP PRDLQFVEVT DVKITIMWTP PESPVTGYRV DVIPVNLPGE HGQRLPVSRN TFAEVTGLSP GVTYHFKVFA VNQGRESKPL TAQQATKLDA PTNLQFINET DTTVIVTWTP PRARIVGYRL TVGLTRGGQP KQYNVGPAAS QYPLRNLQPG SEYAVSLVAV KGNQQSPRVT GVFTTLQPLG SIPHYNTEVT ETTIVITWTP APRIGFKLGV RPSQGGEAPR EVTSESGSIV VSGLTPGVEY VYTISVLRDG QERDAPIVKK VVTPLSPPTN LHLEANPDTG VLTVSWERST TPDITGYRIT TTPTNGQQGY SLEEVVHADQ SSCTFENLSP GLEYNVSVYT VKDDKESVPI SDTIIPEVPQ LTDLSFVDIT DSSIGLRWTP LNSSTIIGYR ITVVAAGEGI PIFEDFVDSS VGYYTVTGLE PGIDYDISVI TLINGGESAP TTLTQQTAVP PPTDLRFTNV GPDTMRVTWA PPSSIELTNL LVRYSPVKNE EDVAELSISP SDNAVVLTNL LPGTEYLVSV SSVYEQHESI PLRGRQKTAL DSPSGIDFSD ITANSFTVHW IAPRATITGY RIRHHPENMG GRPREDRVPP SRNSITLTNL NPGTEYVVSI VALNSKEESL PLVGQQSTVS DVPRDLEVIA ATPTSLLISW DAPAVTVRYY RITYGETGGS SPVQEFTVPG SKSTATISGL KPGVDYTITV YAVTGRGDSP ASSKPVSINY RTEIDKPSQM QVTDVQDNSI SVRWLPSSSP VTGYRVTTAP KNGPGPSKTK TVGPDQTEMT IEGLQPTVEY VVSVYAQNQN GESQPLVQTA VTNIDRPKGL AFTDVDVDSI KIAWESPQGQ VSRYRVTYSS PEDGIHELFP APDGEEETAE LQGLRPGSEY TVSVVALHDD MESQPLIGTQ STTIPAPTNL KFTQVTPTSL TAQWTAPNVQ LTGYRVRVTP KEKTGPMKEI NLAPDSSSVV VSGLMVATKY EVSVYALKDT LTSRPAQGVV TTLENVSPPR RARVTDATET TITISWRTKT ETITGFQVDA IPANGQTPIQ RTIRPDVRSY TITGLQPGTD YKIHLYTLND NARSSPVVID ASTAIDAPSN LRFLATTPNS LLVSWQPPRA RITGYIIKYE KPGSPPREVV PRPRPGVTEA TITGLEPGTE YTIQVIALKN NQKSEPLIGR KKTDELPQLV TLPHPNLHGP EILDVPSTVQ KTPFITNPGY DTGNGIQLPG TSGQQPSLGQ QMIFEEHGFR RTTPPTTATP VRHRPRPYPP NVNEEIQIGH VPRGDVDHHL YPHVVGLNPN ASTGQEALSQ TTISWTPFQE SSEYIISCHP VGIDEEPLQF RVPGTSASAT LTGLTRGATY NIIVEAVKDQ QRQKVREEVV TVGNSVDQGL SQPTDDSCFD PYTVSHYAIG EEWERLSDSG FKLSCQCLGF GSGHFRCDSS KWCHDNGVNY KIGEKWDRQG ENGQMMSCTC LGNGKGEFKC DPHEATCYDD GKTYHVGEQW QKEYLGAICS CTCFGGQRGW RCDNCRRPGA EPGNEGSTAH SYNQYSQRYH QRTNTNVNCP IECFMPLDVQ ADREDSRE
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

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Target Background

Function(From Uniprot)

Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts.; Binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling.

Subcellular Location

Secreted, extracellular space, extracellular matrix.

Tissue Specificity

Plasma FN (soluble dimeric form) is secreted by hepatocytes. Cellular FN (dimeric or cross-linked multimeric forms), made by fibroblasts, epithelial and other cell types, is deposited as fibrils in the extracellular matrix.

Database Links

UNIGENE: Bt.23418

STRING: 9913.ENSBTAP00000010925

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