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Recombinant Bovine Fibroblast growth factor 18 (FGF18)

Recombinant Bovine Fibroblast growth factor 18 (FGF18)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

FGF18

Purity

>85% (SDS-PAGE)

Target Names

FGF18

Uniprot NO.

Q0VCA0

Alternative Names

FGF18Fibroblast growth factor 18; FGF-18; zFGF5

Species

Bos taurus (Bovine)

Source

Yeast

Expression Region

28-207

Target Protein Sequence

EEN VDFRIHVENQ TRARDDVSRK QLRLYQLYSR TSGKHIQVLG RRISARGEDG DKYAQLLVET DTFGSQVRIK GKETEFYLCM NRKGKLVGKP DGTSKECVFI EKVLENNYTA LMSAKYSGWY VGFTKKGRPR KGPKTRENQQ DVHFMKRYPK GQAELQKPFK YTTVTKRSRR IRPTHPG
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Plays an important role in the regulation of cell proliferation, cell differentiation and cell migration. Required for normal ossification and bone development. Stimulates hepatic and intestinal proliferation.

Gene References into Functions

FGF18 is proapoptotic in vivo and may act through a mechanism involving the BBC3-MDM2 pathway. PMID:25411391
FGF8 and FGF18 signal through divergent pathways in ovarian granulosa cells, despite reportedly similar receptor activation patterns. PMID:23707615
these data point to a unique role for FGF18 in signaling from theca cells to granulosa cells and suggest that FGF18 influences the process of atresia in ovarian follicles. PMID:20484739

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Subcellular Location

Secreted.

Protein Families

Heparin-binding growth factors family

Database Links

UNIGENE: Bt.62474

KEGG: bta:533929

STRING: 9913.ENSBTAP00000000139

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