Recombinant Bovine Fatty acid-binding protein, heart (FABP3)

Product Details

Purity
>85% (SDS-PAGE)
Target Names
FABP3
Uniprot NO.
Species
Bos taurus (Bovine)
Source
Yeast
Expression Region
2-133
Target Protein Sequence
VDAFVGTWK LVDSKNFDDY MKSLGVGFAT RQVGNMTKPT TIIEVNGDTV IIKTQSTFKN TEISFKLGVE FDETTADDRK VKSIVTLDGG KLVHVQKWNG QETSLVREMV DGKLILTLTH GTAVCTRTYE KQA
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
Protein Length
Full Length of Mature Protein
Tag Info
N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage
Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.; MDGI reversibly inhibits proliferation of mammary carcinoma cells.
Gene References into Functions
  1. Sequence analysis showed that many transcriptional factor binding sites including TATA-box and CCAAT-box were present on the 5'-flanking region of bovine FABP3, and four CpG islands were found on nucleotides from -891 to +118. PMID:27270359
  2. FABP3 has a role in milk fat synthesis signaling. PMID:24947174
  3. FABP3 gene frequency and SNP genotypes in Holstein-Friesian cows and its relationship with protein and fat content in milk PMID:25474885
  4. Thus, the results of our study suggest that the H-FABP and PSMC1 gene polymorphisms could be used as genetic markers in marker-assisted selection for improving Qinchuan beef cattle PMID:24668675
  5. polymorphisms can be used to select for milk with lower concentrations of saturated fatty acids and higher concentrations of unsaturated fatty acids PMID:23831098
  6. MRF4 and H-FABP genes are associated with growth traits in Qinchuan cattle and related hybrids PMID:20582633
  7. fine mapping of this gene to BTA2q45 by fluorescence in situ hybridization and radiation hybrid mapping PMID:14687081
  8. The results of this study suggest that suggest that SLC27A6, ACSL1, FABP3, AGPAT6, and LPIN1 coordinately regulate the channeling of fatty acids toward copious milk fat synthesis in bovine mammary. PMID:18492828

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Subcellular Location
Cytoplasm. Mitochondrion matrix.
Protein Families
Calycin superfamily, Fatty-acid binding protein (FABP) family
Tissue Specificity
Mammary epithelial cells of developing lobuloalveolar structures and heart.
Database Links

UNIGENE: Bt.4758

KEGG: bta:281758

STRING: 9913.ENSBTAP00000022375

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