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Recombinant Bovine Fatty acid-binding protein, epidermal (FABP5)

Recombinant Bovine Fatty acid-binding protein, epidermal (FABP5)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

FABP5

Uniprot NO.

P55052

Alternative Names

FABP5; Fatty acid-binding protein 5; Differentiation-associated lipid-binding protein LP2; Epidermal-type fatty acid-binding protein; E-FABP; Fatty acid-binding protein; epidermal

Species

Bos taurus (Bovine)

Source

Yeast

Expression Region

2-135

Target Protein Sequence

ATVQQLVGR WRLVESKGFD EYMKEVGVGM ALRKVGAMAK PDCIITSDGK NLSIKTESTL KTTQFSCKLG EKFEETTADG RKTQTVCNFT DGALVQHQEW DGKESTITRK LEDGKLVVVC VMNNVTCTRV YEKVE
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Intracellular carrier for long-chain fatty acids and related active lipids, such as endocannabinoids, that regulate the metabolism and actions of the ligands they bind. In addition to the cytosolic transport, selectively delivers specific fatty acids from the cytosol to the nucleus, wherein they activate nuclear receptors. Delivers retinoic acid to the nuclear receptor peroxisome proliferator-activated receptor delta; which promotes proliferation and survival. May also serve as a synaptic carrier of endocannabinoid at central synapses and thus controls retrograde endocannabinoid signaling. Modulates inflammation by regulating PTGES induction via NF-kappa-B activation, and prostaglandin E2 (PGE2) biosynthesis during inflammation.

Subcellular Location

Cytoplasm. Nucleus. Cell junction, synapse. Cell junction, synapse, postsynaptic density. Secreted.

Protein Families

Calycin superfamily, Fatty-acid binding protein (FABP) family

Tissue Specificity

Most abundant in lens and retina (found in the mueller cells), moderately abundant in heart and testis (found in the Sertoli cells), and present in very low amounts in lung.

Database Links

UNIGENE: Bt.102854

KEGG: bta:281760

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