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Recombinant Bovine Eukaryotic translation initiation factor 4E-binding protein 1 (EIF4EBP1)

Recombinant Bovine Eukaryotic translation initiation factor 4E-binding protein 1 (EIF4EBP1)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

EIF4EBP1

Purity

>85% (SDS-PAGE)

Target Names

EIF4EBP1

Uniprot NO.

Q0P5A7

Alternative Names

EIF4EBP1Eukaryotic translation initiation factor 4E-binding protein 1; 4E-BP1; eIF4E-binding protein 1

Species

Bos taurus (Bovine)

Source

Yeast

Expression Region

2-118

Target Protein Sequence

SGGSSCSQT PSRAIPTTRR VVLADGVQLP PGDYSTTPGG TLFSTTPGGT RIIYDRKFLM ECRNSPVTKT PPRDLPTIPG VTSPTGDEPP TEARQNHLRS SPEDKPAGGE ESQFEMDI
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.

Protein Families

EIF4E-binding protein family

Database Links

UNIGENE: Bt.5389

KEGG: bta:509613

STRING: 9913.ENSBTAP00000039615

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